Festenstein F, Weatherstone R M, Rehahn M
Department of Thoracic Medicine, London Chest Hospital.
J R Soc Med. 1988 Feb;81(2):84-6. doi: 10.1177/014107688808100210.
Five hundred men and 76 women all under the care of one physician at the London Chest Hospital were diagnosed as having bronchogenic carcinoma and admitted to a prospective survey between May 1966 and April 1978. The survey was completed in December 1984 when all but 19 of the 500 men had died. None was lost to follow up. The longest period of surveillance was 18 years 7 months, the shortest 6 years 8 months. The five-year survival of the group of 500 men was 7.6% (38), and 22% (32) for the 145 patients who had had resections. Of the 78 patients (63 men, 15 women) who had small cell carcinoma, only one survived 3 years; the others died in under 2 years, giving a median survival of 5 months. The median survival of the 21 untreated cases in this group of small cell carcinoma was 2 months.
在伦敦胸科医院，由同一位医生负责诊治的500名男性和76名女性被诊断患有支气管源性癌，并于1966年5月至1978年4月期间纳入一项前瞻性研究。该研究于1984年12月完成，此时500名男性中除19人外均已死亡。无一例失访。最长随访期为18年7个月，最短为6年8个月。500名男性患者的五年生存率为7.6%（38例），接受手术切除的145例患者的五年生存率为22%（32例）。在78例小细胞癌患者（63名男性，15名女性）中，只有1例存活超过3年；其他患者在2年内死亡，中位生存期为5个月。该组小细胞癌中21例未接受治疗的患者的中位生存期为2个月。
