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INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters.

作者信息

Kemter Elisabeth, Cohrs Christian M, Schäfer Matthias, Schuster Marion, Steinmeyer Klaus, Wolf-van Buerck Lelia, Wolf Andrea, Wuensch Annegret, Kurome Mayuko, Kessler Barbara, Zakhartchenko Valeri, Loehn Matthias, Ivashchenko Yuri, Seissler Jochen, Schulte Anke M, Speier Stephan, Wolf Eckhard

机构信息

Chair for Molecular Animal Breeding and Biotechnology, Gene Centre, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.

Centre for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.

出版信息

Diabetologia. 2017 Jun;60(6):1152-1156. doi: 10.1007/s00125-017-4250-2. Epub 2017 Mar 18.

DOI:10.1007/s00125-017-4250-2
PMID:28315950
Abstract
摘要

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本文引用的文献

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Endocrinology. 2017 May 1;158(5):1373-1385. doi: 10.1210/en.2016-1184.
2
Alterations in β-Cell Calcium Dynamics and Efficacy Outweigh Islet Mass Adaptation in Compensation of Insulin Resistance and Prediabetes Onset.在胰岛素抵抗和糖尿病前期发病的代偿过程中，β细胞钙动力学改变及效能比胰岛质量适应性变化更为重要。
Diabetes. 2016 Sep;65(9):2676-85. doi: 10.2337/db15-1718. Epub 2016 Apr 8.
3
Engraftment and reversal of diabetes after intramuscular transplantation of neonatal porcine islet-like clusters.
在基于藻酸盐的生物墨水中生物打印的新生猪胰岛样细胞簇的活力和功能
Biomedicines. 2022 Jun 15;10(6):1420. doi: 10.3390/biomedicines10061420.
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Sequential in vivo labeling of insulin secretory granule pools in - transgenic pigs.- 转基因猪胰岛素分泌颗粒库的连续体内标记。
Proc Natl Acad Sci U S A. 2021 Sep 14;118(37). doi: 10.1073/pnas.2107665118.
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The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells.肝细胞分泌的胎球蛋白-A 会破坏胰腺β细胞的功能成熟。
Diabetologia. 2021 Jun;64(6):1358-1374. doi: 10.1007/s00125-021-05435-1. Epub 2021 Mar 25.
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Manipulating the Epigenome in Nuclear Transfer Cloning: Where, When and How.核转移克隆中表观基因组的操作：位置、时间和方式。
Int J Mol Sci. 2020 Dec 28;22(1):236. doi: 10.3390/ijms22010236.
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A decade of experience with genetically tailored pig models for diabetes and metabolic research.用于糖尿病和代谢研究的基因定制猪模型十年经验。
Anim Reprod. 2020 Aug 26;17(3):e20200064. doi: 10.1590/1984-3143-AR2020-0064.
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Integration of nano- and biotechnology for beta-cell and islet transplantation in type-1 diabetes treatment.纳米技术和生物技术在 1 型糖尿病治疗中的胰岛和β细胞移植的整合。
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Large scale isolation, growth, and function of porcine neonatal islet cells.猪新生胰岛细胞的大规模分离、培养及功能研究
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