Zając-Gawlak Izabela, Kłapcińska Barbara, Kroemeke Aleksandra, Pośpiech Dariusz, Pelclová Jana, Přidalová Miroslava
The Jerzy Kukuczka Academy of Physical Education, Mikołowska 72a, 40 065, Katowice, Poland.
Department of Psychology, SWPS University of Social Sciences and Humanities, Chodakowska 19/31, 03-815, Warsaw, Poland.
Biogerontology. 2017 Jun;18(3):357-366. doi: 10.1007/s10522-017-9693-9. Epub 2017 Mar 18.
This study was aimed at the evaluation of relationship between visceral fat area (VFA) and physical activity (PA) with the metabolic syndrome (MetS) risk in the physically active postmenopausal women. A total of 85 attendants of the University of the Third Age (U3A) aged 62.8 ± 5.9 years (median time since menopause 11.8 y), participated in this study. VFA was assessed by bioimpedance method using InBody 720 analyzer. PA was assessed using the ActiGraph GT1 M accelerometer. Fasting levels of serum lipids (TG, HDL), serum glucose, waist circumference (WC) and blood pressure were measured to diagnose MetS according to NCEP-ATP III criteria. In 73 out of 85 participants the VFA exceeded the upper normal level of 100 cm, however, in almost a half of this group (n = 36) with elevated VFA (139.5 ± 26.1 cm on average), only 2 out of 5 criteria for MetS diagnosis were met. Participants were physically active, making on average 10,919 ± 3435 steps/day. The risk of MetS occurrence in women with VFA > 100 cm was twelve times higher (OR 12.33; CI 95% [1.5; 99.8]) than in the group with VFA < 100 cm. The participants from the group with the highest PA level (≥12,500 steps/day) were at almost 4 times lower risk for MetS, than their less active counterparts (OR 3.84; CI 95% [1.27;11.64]). Increased level of VFA is a strong risk factor for the MetS in postmenopausal women, however high level of regular PA above the threshold of 12,500 steps/day may substantially reduce it.
本研究旨在评估身体活跃的绝经后女性内脏脂肪面积（VFA）和身体活动（PA）与代谢综合征（MetS）风险之间的关系。共有85名第三年龄大学（U3A）的参与者，年龄为62.8±5.9岁（绝经后中位时间为11.8年），参与了本研究。使用InBody 720分析仪通过生物阻抗法评估VFA。使用ActiGraph GT1M加速度计评估PA。根据NCEP-ATP III标准，测量空腹血脂水平（TG、HDL）、血糖、腰围（WC）和血压以诊断MetS。85名参与者中有73人的VFA超过正常上限100厘米，然而，在这组VFA升高的人群中（平均139.5±26.1厘米），几乎一半（n = 36）仅满足MetS诊断5项标准中的2项。参与者身体活跃，平均每天步数为10,9,19±3,435步。VFA>100厘米的女性发生MetS的风险比VFA<100厘米的组高12倍（OR 12.33；95%CI[1.5；99.8]）。PA水平最高组（≥12,500步/天）的参与者患MetS的风险比活动较少的同龄人低近4倍（OR 3.84；95%CI[1.27；11.64]）。VFA水平升高是绝经后女性患MetS的强烈风险因素，然而，每天步数超过12,500步阈值的高水平规律PA可能会大幅降低该风险。
