Geramizadeh Bita, Owen David A
Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran ; Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Deptartment of Pathology, Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada.
Middle East J Dig Dis. 2017 Jan;9(1):5-11. doi: 10.15171/mejdd.2016.45.
Endoscopic mucosal resection (EMR) is a non-invasive alternative to surgery that is now frequently used for resection of early lesions in both upper and lower parts of the gastrointestinal (GI) tract. One of the main advantages of these techniques is providing tissue for histopathological examination. Pathological examination of endoscopically resected specimens of GI tract is a crucial component of these procedures and is useful for prediction of both the risk of metastasis and lymph node involvement. As the first step, it is very important for the pathologist to handle the EMR gross specimen in the correct way: it should be oriented, and then the margins should be labeled and inked accurately before fixation. In the second step, the EMR pathological report should include all the detailed information about the diagnosis, grading, depth of invasion (mucosa only or submucosal involvement), status of the margins, and the presence or absence of lymphovascular invasion. The current literature (PubMed and Google Scholar) was searched for the words "endoscopic mucosal resection" to find all relevant publications about this technique with emphasis on the pathologist responsibilities.
内镜黏膜切除术（EMR）是一种非侵入性的手术替代方法，目前常用于切除胃肠道（GI）上、下部位的早期病变。这些技术的主要优点之一是能够提供组织用于组织病理学检查。胃肠道内镜切除标本的病理检查是这些手术的关键组成部分，对于预测转移风险和淋巴结受累情况很有用。第一步，病理学家以正确方式处理EMR大体标本非常重要：应将其定向，然后在固定前准确标记并对切缘进行墨染。第二步，EMR病理报告应包括有关诊断、分级、浸润深度（仅黏膜或黏膜下层受累）、切缘状态以及是否存在淋巴管浸润的所有详细信息。检索了当前文献（PubMed和谷歌学术）中“内镜黏膜切除术”一词，以查找有关该技术的所有相关出版物，重点是病理学家的职责。
