• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

4种市售自膨式颅内支架物理特性的台式比较

Bench-top Comparison of Physical Properties of 4 Commercially-Available Self-Expanding Intracranial Stents.

作者信息

Cho Su-Hee, Jo Won-Il, Jo Ye-Eun, Yang Ku Hyun, Park Jung Cheol, Lee Deok Hee

机构信息

Department of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Angiovention, Ilsan, Korea.

出版信息

Neurointervention. 2017 Mar;12(1):31-39. doi: 10.5469/neuroint.2017.12.1.31. Epub 2017 Mar 6.

DOI:10.5469/neuroint.2017.12.1.31
PMID:28316867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5355459/
Abstract

PURPOSE

To better understand the performance of four commercially available neurovascular stents in intracranial aneurysm embolization, the stents were compared in terms of their basic morphological and mechanical properties.

MATERIALS AND METHODS

Four different types of stents that are currently being used for cerebral aneurysm embolization were prepared (two stents per type). Two were laser-cut stents (Neuroform and Enterprise) and two were braided from a single nitinol wire (LEO and LVIS stents). All were subjected to quantitative measurements of stent size, pore density, metal coverage, the force needed to load, push, and deploy the stent, radial force on deployment, surface roughness, and corrosion resistance.

RESULTS

Compared to their nominal diameters, all stents had greater diameters after deployment. The length generally decreased after deployment. This was particularly marked in the braided stents. The braided stents also had higher pore densities than the laser-cut stents. Metal coverage was highest in the LEO stent (14%) and lowest in the Enterprise stent (5%). The LIVS stent had the highest microcatheter loading force (81.5 gf). The LEO stent had the highest passage force (55.0 gf) and deployment force (78.9 gf). The LVIS and LEO stents had the highest perpendicular (37.1 gf) and circumferential (178.4 gf) radial forces, respectively. The Enterprise stent had the roughest stent wire, followed by the LVIS, LEO, and Neuroform stents.

CONCLUSION

The four neurovascular stent types differed in terms of morphological and physical characteristics. An understanding of this diversity may help to decide which stent is most suitable for specific clinical situations.

摘要

目的

为了更好地了解四种市售神经血管支架在颅内动脉瘤栓塞中的性能,对这些支架的基本形态和力学性能进行了比较。

材料与方法

准备了四种目前用于脑动脉瘤栓塞的不同类型的支架(每种类型两个支架)。两个是激光切割支架(Neuroform和Enterprise),两个是由单根镍钛诺丝编织而成(LEO和LVIS支架)。对所有支架进行了支架尺寸、孔隙密度、金属覆盖率、加载、推送和展开支架所需的力、展开时的径向力、表面粗糙度和耐腐蚀性的定量测量。

结果

与标称直径相比,所有支架展开后的直径都更大。展开后长度一般会减小。这在编织支架中尤为明显。编织支架的孔隙密度也高于激光切割支架。金属覆盖率在LEO支架中最高(14%),在Enterprise支架中最低(5%)。LIVS支架的微导管加载力最高(81.5 gf)。LEO支架的通过力最高(55.0 gf)和展开力最高(78.9 gf)。LVIS和LEO支架的垂直径向力(37.1 gf)和周向径向力(178.4 gf)分别最高。Enterprise支架的支架丝最粗糙,其次是LVIS、LEO和Neuroform支架。

结论

四种神经血管支架类型在形态和物理特性方面存在差异。了解这种多样性可能有助于确定哪种支架最适合特定的临床情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/6d1f1aea39b9/ni-12-31-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/89d5eaa89a0d/ni-12-31-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/a1c921e9db28/ni-12-31-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/55faa67dc0d0/ni-12-31-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/86fcbba87afb/ni-12-31-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/6d1f1aea39b9/ni-12-31-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/89d5eaa89a0d/ni-12-31-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/a1c921e9db28/ni-12-31-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/55faa67dc0d0/ni-12-31-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/86fcbba87afb/ni-12-31-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4925/5355459/6d1f1aea39b9/ni-12-31-g005.jpg

相似文献

1
Bench-top Comparison of Physical Properties of 4 Commercially-Available Self-Expanding Intracranial Stents.4种市售自膨式颅内支架物理特性的台式比较
Neurointervention. 2017 Mar;12(1):31-39. doi: 10.5469/neuroint.2017.12.1.31. Epub 2017 Mar 6.
2
Comparison of the Physical Characteristics of Support Stents for Cerebral Aneurysm Embolization.脑动脉瘤栓塞术支撑支架物理特性的比较
J Neuroendovasc Ther. 2021;15(12):778-786. doi: 10.5797/jnet.oa.2020-0167. Epub 2021 Mar 27.
3
The Geometry of Y-Stent Configurations Used for Wide-Necked Aneurysm Treatment: Analyzing Double-Barrel Stents In Vitro Using Flat-Panel Computed Tomography.用于治疗宽颈动脉瘤的 Y 型支架构型的几何形状:使用平板计算机断层扫描对双筒支架进行体外分析。
World Neurosurg. 2021 Jul;151:e363-e371. doi: 10.1016/j.wneu.2021.04.042. Epub 2021 Apr 19.
4
Preliminary use of the Leo stent in the endovascular treatment of wide-necked cerebral aneurysms.Leo 支架在宽颈颅内动脉瘤血管内治疗中的初步应用。
World Neurosurg. 2010 Apr;73(4):379-84. doi: 10.1016/j.wneu.2010.01.019.
5
Stent-assisted coiling of cerebral aneurysms: a single-center clinical and angiographic analysis.支架辅助弹簧圈栓塞治疗颅内动脉瘤:单中心临床及血管造影分析。
J Neurointerv Surg. 2018 Jul;10(7):687-692. doi: 10.1136/neurintsurg-2017-013272. Epub 2017 Nov 16.
6
Feasibility of insertion of a microcatheter through a Y-stent in coil embolization of cerebral aneurysms and its detailed geometry by micro-computed tomography.通过Y形支架插入微导管用于脑动脉瘤弹簧圈栓塞术的可行性及其通过微型计算机断层扫描得到的详细几何结构
Acta Neurochir (Wien). 2014 Jan;156(1):39-43. doi: 10.1007/s00701-013-1925-4. Epub 2013 Nov 5.
7
An experimental evaluation of the mechanics of bare and polymer-covered self-expanding wire braided stents.裸金属及聚合物涂层自膨式编织支架力学性能的实验评估
J Mech Behav Biomed Mater. 2020 Mar;103:103549. doi: 10.1016/j.jmbbm.2019.103549. Epub 2019 Nov 21.
8
Does stent type impact coil embolization outcomes in extended follow-up of small-sized aneurysms (< 10 mm)?在小型动脉瘤(<10毫米)的长期随访中,支架类型是否会影响弹簧圈栓塞的结果?
Neuroradiology. 2018 Jul;60(7):747-756. doi: 10.1007/s00234-018-2022-4. Epub 2018 Apr 20.
9
Assisted coiling using LEO Baby or LVIS Jr stents: Report of six cases.使用LEO Baby或LVIS Jr支架进行辅助栓塞:6例报告。
Interv Neuroradiol. 2015 Oct;21(5):566-74. doi: 10.1177/1591019915590098. Epub 2015 Jun 26.
10
Elective treatment of saccular and broad-necked intracranial aneurysms using a closed-cell nitinol stent (Leo).使用闭合型镍钛诺支架(Leo)对囊状和宽颈颅内动脉瘤进行择期治疗。
Neurosurgery. 2006 Mar;58(3):443-50; discussion 443-50. doi: 10.1227/01.NEU.0000197103.10364.0C.

引用本文的文献

1
Y-stent-assisted coiling with pEGASUS stents for intracranial bifurcation aneurysms: A multi-center retrospective study.使用PEGASUS支架辅助Y型支架栓塞治疗颅内分叉部动脉瘤:一项多中心回顾性研究。
Interv Neuroradiol. 2025 Aug 1:15910199251360143. doi: 10.1177/15910199251360143.
2
VIVA Stent Preclinical Evaluation in Swine: A Novel Cerebral Venous Stent with a Unique Delivery System.VIVA支架在猪体内的临床前评估:一种具有独特输送系统的新型脑静脉支架。
J Clin Med. 2025 Jul 3;14(13):4721. doi: 10.3390/jcm14134721.
3
LEO or LEO baby within enterprise overlapping stents combined with coil embolization treatment for ruptured vertebrobasilar artery dissecting aneurysms.

本文引用的文献

1
Stent usage in the treatment of intracranial aneurysms: past, present and future.支架在颅内动脉瘤治疗中的应用:过去、现在和未来。
J Neurol Neurosurg Psychiatry. 2013 Mar;84(3):244-53. doi: 10.1136/jnnp-2011-302007. Epub 2012 Nov 8.
2
Stents and flow diverters in the treatment of aneurysms: device deformation in vivo may alter porosity and impact efficacy.支架和血流导向装置治疗动脉瘤:体内器械变形可能改变孔隙率并影响疗效。
Neuroradiology. 2013 Jan;55(1):85-92. doi: 10.1007/s00234-012-1082-0. Epub 2012 Aug 16.
3
Stent application for the treatment of cerebral aneurysms.
在企业重叠支架联合弹簧圈栓塞治疗破裂性椎基底动脉夹层动脉瘤中使用LEO或LEO婴儿型支架
Sci Rep. 2025 Jul 11;15(1):25153. doi: 10.1038/s41598-025-11035-5.
4
Hemifacial Spasm Caused by Posterior Inferior Cerebellar Artery Compression due to Vertebral Artery Aneurysm: Management with Stent-Assisted Coil Embolization.椎动脉动脉瘤致小脑后下动脉压迫引起的半面痉挛:支架辅助弹簧圈栓塞治疗
Neurointervention. 2025 Jul;20(2):109-113. doi: 10.5469/neuroint.2025.00073. Epub 2025 Mar 7.
5
Stable and Thin-Polymer-Based Modification of Neurovascular Stents with 2-Methacryloyloxyethyl Phosphorylcholine Polymer for Antithrombogenicity.用2-甲基丙烯酰氧乙基磷酰胆碱聚合物对神经血管支架进行基于稳定且薄聚合物的修饰以实现抗血栓形成
Bioengineering (Basel). 2024 Aug 15;11(8):833. doi: 10.3390/bioengineering11080833.
6
Single Neuroform Atlas stent: a reliable approach for treating complex wide-neck bifurcated aneurysms.单枚Neuroform Atlas支架:治疗复杂宽颈分叉动脉瘤的可靠方法。
Front Neurol. 2024 Jul 16;15:1391799. doi: 10.3389/fneur.2024.1391799. eCollection 2024.
7
Safety and effectiveness of LEO stents for dual stent-assisted embolization combined with IA and IV intra-procedural infusion of tirofiban in the treatment of wide-necked intracranial bifurcation aneurysms.LEO支架在双支架辅助栓塞联合动脉内及静脉内术中输注替罗非班治疗宽颈颅内分叉动脉瘤中的安全性和有效性。
Front Neurol. 2024 Jul 10;15:1393310. doi: 10.3389/fneur.2024.1393310. eCollection 2024.
8
The Safety and Efficacy of Leo Stents with Coiling or Alone for Anterior Cerebral Artery Aneurysms.载瘤动脉支架辅助弹簧圈栓塞或单纯弹簧圈栓塞治疗大脑前动脉动脉瘤的安全性和有效性。
Curr Neurovasc Res. 2024;20(5):560-567. doi: 10.2174/0115672026271147231130111233.
9
Appraisal of the Flow Diversion Effect Provided by Braided Intracranial Stents.编织型颅内支架提供的血流导向效果评估
J Clin Med. 2024 Jun 11;13(12):3409. doi: 10.3390/jcm13123409.
10
Stent plus balloon-assisted coiling with low-profile braided stents in the treatment of complex wide-necked intracranial bifurcation aneurysms.支架辅助球囊成形术联合微导管编织支架治疗复杂宽颈颅内分叉部动脉瘤。
Neuroradiol J. 2024 Oct;37(5):603-610. doi: 10.1177/19714009241247462. Epub 2024 Apr 15.
用于治疗脑动脉瘤的支架应用。
Neurointervention. 2011 Aug;6(2):53-70. doi: 10.5469/neuroint.2011.6.2.53. Epub 2011 Aug 31.
4
Delivery technique plays an important role in determining vessel wall apposition of the Enterprise self-expanding intracranial stent.输送技术在确定 Enterprise 自膨式颅内支架的血管壁贴壁方面起着重要作用。
J Neurointerv Surg. 2011 Dec 1;3(4):340-3. doi: 10.1136/jnis.2010.004499. Epub 2011 Mar 9.
5
Comparison of devices used for stent-assisted coiling of intracranial aneurysms.比较用于颅内动脉瘤支架辅助弹簧圈栓塞的装置。
PLoS One. 2011;6(9):e24875. doi: 10.1371/journal.pone.0024875. Epub 2011 Sep 22.
6
Radial force measurements in carotid stents: influence of stent design and length of the lesion.颈动脉支架的径向力测量:支架设计和病变长度的影响。
J Vasc Interv Radiol. 2011 May;22(5):661-6. doi: 10.1016/j.jvir.2011.01.450.
7
A comparison of functional and physical properties of self-expanding intracranial stents [Neuroform3, Wingspan, Solitaire, Leo+, Enterprise].自膨式颅内支架[Neuroform3、Wingspan、Solitaire、Leo+、Enterprise]的功能和物理特性比较
Minim Invasive Neurosurg. 2011 Feb;54(1):21-8. doi: 10.1055/s-0031-1271681. Epub 2011 Apr 19.
8
Comparison of carotid stents: an in-vitro experiment focusing on stent design.颈动脉支架的比较:一项聚焦于支架设计的体外实验。
J Endovasc Ther. 2009 Apr;16(2):168-77. doi: 10.1583/08-2539.1.
9
A new self-expandable nitinol stent for the treatment of wide-neck aneurysms: initial clinical experience.一种用于治疗宽颈动脉瘤的新型自膨胀镍钛合金支架:初步临床经验。
AJNR Am J Neuroradiol. 2008 Aug;29(7):1405-8. doi: 10.3174/ajnr.A1104. Epub 2008 Apr 24.
10
Physical properties of endovascular stents: an experimental comparison.血管内支架的物理特性:一项实验比较
J Vasc Interv Radiol. 2000 May;11(5):645-54. doi: 10.1016/s1051-0443(07)61620-0.