• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

英国关于睾酮缺乏的政策声明。

UK policy statements on testosterone deficiency.

作者信息

Hackett Geoffrey, Kirby Michael, Edwards David, Jones T Hugh, Rees Jonathan, Muneer Asif

机构信息

Good Hope Hospital, Birmingham, UK.

University of Bedfordshire, Luton, UK.

出版信息

Int J Clin Pract. 2017 Mar;71(3-4). doi: 10.1111/ijcp.12901. Epub 2017 Mar 20.

DOI:10.1111/ijcp.12901
PMID:28318076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5573939/
Abstract

To address widespread media and scientific concerns over the appropriate treatment of TDS with Testosterone Therapy (T Therapy), the Executive Committee of the British Society for Sexual Medicine developed eight consensus statements, based on current scientific evidence to address these controversial issues. These statements were in no-way designed to replace the published evidence-based guidelines on the subject developed by various professional organisations, but to provide specific answers to several current controversial issues. This review examined evidence from Medline, EMBASE and Cochrane searches on HG, T Therapy and cardiovascular safety from May 2005 to May 2015, which revealed 1714 articles, with 52 clinical trials and 32 placebo-controlled randomised controlled trials. The task force developed the following eight key statements.

摘要

为应对媒体和科学界对睾酮疗法(T疗法)治疗迟发性性腺功能减退(TDS)的适当性的广泛关注,英国性医学学会执行委员会根据当前科学证据制定了八项共识声明,以解决这些有争议的问题。这些声明绝非旨在取代各专业组织制定的关于该主题的已发表的循证指南,而是为当前几个有争议的问题提供具体答案。本综述检索了2005年5月至2015年5月期间Medline、EMBASE和Cochrane数据库中关于迟发性性腺功能减退、睾酮疗法和心血管安全性的证据,共检索到1714篇文章,其中有52项临床试验和32项安慰剂对照随机对照试验。特别工作组制定了以下八项关键声明。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0b6/5573939/cc1349d60b2d/IJCP-71-na-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0b6/5573939/46a9112c92e1/IJCP-71-na-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0b6/5573939/5de28acd0cc9/IJCP-71-na-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0b6/5573939/cc1349d60b2d/IJCP-71-na-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0b6/5573939/46a9112c92e1/IJCP-71-na-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0b6/5573939/5de28acd0cc9/IJCP-71-na-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0b6/5573939/cc1349d60b2d/IJCP-71-na-g003.jpg

相似文献

1
UK policy statements on testosterone deficiency.英国关于睾酮缺乏的政策声明。
Int J Clin Pract. 2017 Mar;71(3-4). doi: 10.1111/ijcp.12901. Epub 2017 Mar 20.
2
British Society for Sexual Medicine Guidelines on Adult Testosterone Deficiency, With Statements for UK Practice.英国性医学学会成人睾丸功能减退症指南,附英国实践声明。
J Sex Med. 2017 Dec;14(12):1504-1523. doi: 10.1016/j.jsxm.2017.10.067.
3
Quality of professional society guidelines and consensus conference statements in critical care.重症监护领域专业学会指南及共识会议声明的质量
Crit Care Med. 2008 Apr;36(4):1049-58. doi: 10.1097/CCM.0b013e31816a01ec.
4
The British Society for Sexual Medicine Guidelines on Male Adult Testosterone Deficiency, with Statements for Practice.英国性医学学会《成人男性睾酮缺乏指南及实践声明》
World J Mens Health. 2023 Jul;41(3):508-537. doi: 10.5534/wjmh.221027. Epub 2023 Feb 22.
5
Guidelines, clinical practice recommendations, position papers and consensus statements: definition, preparation, role and application.指南、临床实践建议、立场文件和共识声明:定义、制定、作用及应用。
Ultraschall Med. 2014 Oct;35(5):395-9. doi: 10.1055/s-0034-1385158. Epub 2014 Oct 15.
6
The Quality of Practice Committee of the RCPCH.皇家儿科医学院实践质量委员会
Arch Dis Child. 2005 Sep;90(9):888-91. doi: 10.1136/adc.2004.064253.
7
[Guidelines for specialized nutritional and metabolic support in the critically-ill patient. Update. Consensus of the Spanish Society of Intensive Care Medicine and Coronary Units-Spanish Society of Parenteral and Enteral Nutrition (SEMICYUC-SENPE): introduction and methodology].[危重症患者特殊营养与代谢支持指南。更新版。西班牙重症监护医学与冠心病监护病房学会 - 西班牙肠外与肠内营养学会(SEMICYUC - SENPE)共识:引言与方法]
Med Intensiva. 2011 Nov;35 Suppl 1:1-6. doi: 10.1016/S0210-5691(11)70001-8.
8
[The meaning of 'consensus' in the context of guidelines--an introduction into the problem].[指南背景下“共识”的含义——问题介绍]
Z Arztl Fortbild Qualitatssich. 2007;101(2):85-7. doi: 10.1016/j.zgesun.2007.01.001.
9
Endocrine aspects of sexual dysfunction in men.男性性功能障碍的内分泌方面
J Sex Med. 2004 Jul;1(1):69-81. doi: 10.1111/j.1743-6109.2004.10111.x.
10
Fundamental Concepts Regarding Testosterone Deficiency and Treatment: International Expert Consensus Resolutions.关于睾酮缺乏和治疗的基本概念:国际专家共识决议。
Mayo Clin Proc. 2016 Jul;91(7):881-96. doi: 10.1016/j.mayocp.2016.04.007. Epub 2016 Jun 21.

引用本文的文献

1
Glycopeptide Promotes Testosterone Synthesis and Glucose Metabolism in Leydig Cells of the Testis.糖肽促进睾丸间质细胞中睾酮的合成和葡萄糖代谢。
Biomolecules. 2025 Mar 17;15(3):425. doi: 10.3390/biom15030425.
2
Diagnosis and treatment of hypogonadism in men seeking to preserve fertility - what are the options?寻求保留生育能力的男性性腺功能减退的诊断与治疗——有哪些选择?
Int J Impot Res. 2025 Feb;37(2):109-113. doi: 10.1038/s41443-024-00897-4. Epub 2024 Apr 30.
3
The British Society for Sexual Medicine Guidelines on Male Adult Testosterone Deficiency, with Statements for Practice.

本文引用的文献

1
Erythrocytosis and Polycythemia Secondary to Testosterone Replacement Therapy in the Aging Male.老年男性睾酮替代治疗继发的红细胞增多症和真性红细胞增多症
Sex Med Rev. 2015 Apr;3(2):101-112. doi: 10.1002/smrj.43. Epub 2015 Dec 2.
2
Survival and cardiovascular events in men treated with testosterone replacement therapy: an intention-to-treat observational cohort study.接受睾酮替代治疗的男性的生存和心血管事件:一项意向治疗观察性队列研究。
Lancet Diabetes Endocrinol. 2016 Jun;4(6):498-506. doi: 10.1016/S2213-8587(16)00112-1. Epub 2016 May 7.
3
An update on the role of testosterone replacement therapy in the management of hypogonadism.
英国性医学学会《成人男性睾酮缺乏指南及实践声明》
World J Mens Health. 2023 Jul;41(3):508-537. doi: 10.5534/wjmh.221027. Epub 2023 Feb 22.
4
Expert Opinion on the Diagnosis and Management of Male Hypogonadism in India.印度男性性腺功能减退症诊断与管理专家意见
Int J Endocrinol. 2023 Feb 22;2023:4408697. doi: 10.1155/2023/4408697. eCollection 2023.
5
Improving the annual monitoring rates of testosterone replacement therapy patients in primary care.提高初级保健中睾酮替代疗法患者的年度监测率。
BMJ Open Qual. 2022 Aug;11(3). doi: 10.1136/bmjoq-2021-001784.
6
Non-obstructive azoospermia: current and future perspectives.非梗阻性无精子症:现状与未来展望
Fac Rev. 2021 Jan 26;10:7. doi: 10.12703/r/10-7. eCollection 2021.
7
Testosterone and the Heart.睾酮与心脏
Eur Cardiol. 2019 Jul 11;14(2):103-110. doi: 10.15420/ecr.2019.13.1. eCollection 2019 Jul.
睾酮替代疗法在性腺功能减退管理中的作用的最新进展。
Ther Adv Urol. 2016 Apr;8(2):147-60. doi: 10.1177/1756287215617648. Epub 2015 Dec 9.
4
Serum testosterone, testosterone replacement therapy and all-cause mortality in men with type 2 diabetes: retrospective consideration of the impact of PDE5 inhibitors and statins.2型糖尿病男性患者的血清睾酮、睾酮替代疗法与全因死亡率:对磷酸二酯酶5抑制剂和他汀类药物影响的回顾性思考
Int J Clin Pract. 2016 Mar;70(3):244-53. doi: 10.1111/ijcp.12779. Epub 2016 Feb 24.
5
Effects of Testosterone Treatment in Older Men.睾酮治疗对老年男性的影响。
N Engl J Med. 2016 Feb 18;374(7):611-24. doi: 10.1056/NEJMoa1506119.
6
Testosterone and Cardiovascular Disease.睾酮与心血管疾病。
J Am Coll Cardiol. 2016 Feb 9;67(5):545-57. doi: 10.1016/j.jacc.2015.12.005.
7
Impact of Testosterone Replacement Therapy on Myocardial Infarction, Stroke, and Death in Men With Low Testosterone Concentrations in an Integrated Health Care System.在一个综合医疗保健系统中,睾酮替代疗法对睾酮浓度低的男性发生心肌梗死、中风和死亡的影响。
Am J Cardiol. 2016 Mar 1;117(5):794-9. doi: 10.1016/j.amjcard.2015.11.063. Epub 2015 Dec 13.
8
THERAPY OF ENDOCRINE DISEASE: Testosterone supplementation and body composition: results from a meta-analysis study.内分泌疾病治疗学:睾酮补充与身体成分:一项荟萃分析研究的结果。
Eur J Endocrinol. 2016 Mar;174(3):R99-116. doi: 10.1530/EJE-15-0262. Epub 2015 Nov 4.
9
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY POSITION STATEMENT ON THE ASSOCIATION OF TESTOSTERONE AND CARDIOVASCULAR RISK.美国临床内分泌医师协会与美国内分泌学会关于睾酮与心血管风险关联的立场声明
Endocr Pract. 2015 Sep;21(9):1066-73. doi: 10.4158/EP14434.PS.
10
Normalization of testosterone level is associated with reduced incidence of myocardial infarction and mortality in men.睾酮水平正常化与男性心肌梗死和死亡率的降低有关。
Eur Heart J. 2015 Oct 21;36(40):2706-15. doi: 10.1093/eurheartj/ehv346. Epub 2015 Aug 6.