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初次全膝关节置换术后体重增加与无菌性松动翻修时间加快相关。

Weight Gain After Primary Total Knee Arthroplasty Is Associated With Accelerated Time to Revision for Aseptic Loosening.

作者信息

Lim Chin Tat, Goodman Stuart B, Huddleston James I, Harris Alex H S, Bhowmick Subhrojyoti, Maloney William J, Amanatullah Derek F

机构信息

Department of Orthopaedic Surgery, Stanford University, Stanford, California; Department of Orthopaedic Surgery, Stanford University School of Medicine, Redwood City, California; Department of Orthopaedic Surgery, National University Hospital, Singapore.

Department of Orthopaedic Surgery, Stanford University, Stanford, California; Department of Orthopaedic Surgery, Stanford University School of Medicine, Redwood City, California.

出版信息

J Arthroplasty. 2017 Jul;32(7):2167-2170. doi: 10.1016/j.arth.2017.02.026. Epub 2017 Feb 20.

Abstract

BACKGROUND

Obesity is a major health problem worldwide and is associated with complications after total knee arthroplasty (TKA). It remains unknown whether a change in body mass index (BMI) after primary TKA affects the reasons for revision TKA or the time to revision TKA.

METHODS

A total of 160 primary TKAs referred to an academic tertiary center for revision TKA were retrospectively stratified according to change in BMI from the time of their primary TKA to revision TKA. The association between change in BMI and time to revision was also analyzed according to indication for revision of TKA using Pearson's chi-square test.

RESULTS

The mean change in BMI from primary to revision TKA was 0.82 ± 3.5 kg/m. Maintaining a stable weight after primary TKA was protective against late revision TKA for any reason (P = .004). Patients who failed to reduce their BMI were revised for aseptic loosening earlier, at less than 5 years (P = .020), whereas those who reduced their BMI were revised later, at over 10 years (P = .004).

CONCLUSION

Maintaining weight after primary TKA is protective against later revision TKA for any reason but failure to reduce weight after primary TKA is a risk factor for early revision TKA for aseptic loosening and osteolysis. Orthopedic surgeons should recommend against weight gain after primary TKA to reduce the risk of an earlier revision TKA in the event that a revision TKA is indicated.

摘要

背景

肥胖是全球主要的健康问题,且与全膝关节置换术(TKA)后的并发症相关。初次TKA后体重指数(BMI)的变化是否会影响翻修TKA的原因或翻修TKA的时间尚不清楚。

方法

对转诊至一家学术三级中心进行翻修TKA的160例初次TKA病例,根据其从初次TKA到翻修TKA期间BMI的变化进行回顾性分层。还使用Pearson卡方检验,根据TKA翻修指征分析BMI变化与翻修时间之间的关联。

结果

从初次TKA到翻修TKA,BMI的平均变化为0.82±3.5kg/m²。初次TKA后保持体重稳定可预防因任何原因导致的晚期翻修TKA(P = 0.004)。未能降低BMI的患者因无菌性松动在不到5年时更早接受翻修(P = 0.020),而那些降低了BMI的患者则在超过10年时更晚接受翻修(P = 0.004)。

结论

初次TKA后保持体重可预防因任何原因导致的后期翻修TKA,但初次TKA后未能减轻体重是早期因无菌性松动和骨溶解而进行翻修TKA的危险因素。骨科医生应建议患者在初次TKA后避免体重增加,以降低在需要进行翻修TKA时早期翻修的风险。

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