Khaĭsman E B, Arefolov V A, Malikova L A
Biull Eksp Biol Med. 1988 Mar;105(3):302-5.
The mediator activity of the peripheral catecholaminergic systems (the adrenergic nerves of dura mater and the concentrations of noradrenaline and adrenaline in the adrenals of rats) during dynamic and immobilization stress was investigated with the help of fluorescent microscopy and spectrofluorometry. Neuropeptides--dalargin and another enkephalin analog--were injected intraperitoneally, 150 mg/kg. A visible antistress action of these neuropeptides has been demonstrated, it was more marked after treatment with dalargin. The role of peripheral catecholaminergic system in the mechanism of stress-protective effects of neuropeptides is discussed.
借助荧光显微镜和荧光分光光度法，研究了动态应激和制动应激期间外周儿茶酚胺能系统（硬脑膜的肾上腺素能神经以及大鼠肾上腺中去甲肾上腺素和肾上腺素的浓度）的介质活性。以150毫克/千克的剂量腹腔注射神经肽——达朗金和另一种脑啡肽类似物。已证实这些神经肽具有明显的抗应激作用，用达朗金治疗后作用更显著。讨论了外周儿茶酚胺能系统在神经肽应激保护作用机制中的作用。
