Gulyaeva N V
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, 117485, Russia.
Biochemistry (Mosc). 2017 Mar;82(3):237-242. doi: 10.1134/S0006297917030014.
Biochemical processes in synapses and other neuronal compartments underlie neuroplasticity (functional and structural alterations in the brain enabling adaptation to the environment, learning, memory, as well as rehabilitation after brain injury). This basic molecular level of brain plasticity covers numerous specific proteins (enzymes, receptors, structural proteins, etc.) participating in many coordinated and interacting signal and metabolic processes, their modulation forming a molecular basis for brain plasticity. The articles in this issue are focused on different "hot points" in the research area of biochemical mechanisms supporting neuroplasticity.
突触和其他神经细胞区室中的生化过程是神经可塑性(大脑中的功能和结构改变,使大脑能够适应环境、学习、记忆以及脑损伤后的康复)的基础。大脑可塑性的这一基本分子水平涵盖了众多参与许多协调和相互作用的信号及代谢过程的特定蛋白质(酶、受体、结构蛋白等),它们的调节形成了大脑可塑性的分子基础。本期的文章聚焦于支持神经可塑性的生化机制研究领域的不同“热点”。