Study of light scattering using C-Quant in patients with Fuchs' endothelial dystrophy: A pilot study.

OBJECTIVE

The purpose of this study was to determine the light scattering in patients with Fuchs' endothelial dystrophy without clinically significant corneal oedema, and evaluate its relationship with endothelial cell count, corneal thickness, and corneal biomechanical parameters.

MATERIALS AND METHODS

The values of light scattering were measured by C-Quant (Oculus Optikgeräte GmbH, Germany) in 32 eyes of 17 patients diagnosed with Fuchs' endothelial dystrophy without clinically significant corneal oedema. Corneal biomechanical properties were determined using ORA (ocular response) and Corvis ST (tonometry).

RESULTS

A light scattering value outside the normal range was observed in 93.8% of eyes studied. No statistically significant association (P>.05) was found between the values of the measured light scattering by C-Quant and endothelial count, pachymetry, or corneal biomechanical properties.

CONCLUSIONS

In this study, changes were found in the values of light scattering values of patients with corneal Fuchs' endothelial dystrophy. This change does not appear to correlate significantly with disease severity.