Muthukrishnan Arvind, Bijai Kumar Laliytha
Department of Oral Medicine and Radiology, Saveetha University Saveetha Dental College, Chennai, Tamil Nadu, India.
Saveetha University Saveetha Dental College, Chennai, Tamil Nadu, India.
BMJ Case Rep. 2017 Mar 20;2017:bcr2016218654. doi: 10.1136/bcr-2016-218654.
Potentially malignant disorders (PMD) have a high risk of malignant transformation. Habits such as tobacco and alcohol use predispose to PMD and subsequently to an oral carcinoma. Oral squamous cell carcinoma (OSCC) can occur even without the usage of tobacco. Occupational exposure to actinic rays may predispose to the development of OSCC in the lip. People who are involved in farming or those exposed to an environmental background radiation, such as ultraviolet rays, develop a PMD called actinic cheilosis. A high proportion of patients with actinic cheilosis develop an oral carcinoma when not diagnosed and treated in early stages. This case depicts the clinical and histological changes in a 61-year-old Indian man with actinic cheilosis.
潜在恶性疾病（PMD）具有很高的恶变风险。吸烟和饮酒等习惯易引发PMD，进而导致口腔癌。即使不吸烟，也可能发生口腔鳞状细胞癌（OSCC）。职业性暴露于光化射线可能易患唇部OSCC。从事农业的人或暴露于环境背景辐射（如紫外线）的人会患上一种称为光化性唇炎的PMD。光化性唇炎患者中很大一部分人若在早期未得到诊断和治疗，就会发展为口腔癌。本病例描述了一名61岁患有光化性唇炎的印度男性的临床和组织学变化。
