Department of Plastic and Reconstructive Surgery, Sapienza University, Rome, Italy.
Anticancer Res. 2012 Apr;32(4):1543-6.
Lip cancer is the most frequent tumor of the oral-maxillary region. A high incidence of lip cancer has been reported among the Italian population over the past decade.
This retrospective study analyzes epidemiological data and risk factors for lip cancer among patients who presented to our department between 2000-2010. Statistical analysis for this study was calculated employing Student T and χ-square tests.
Of 540 cases, most were found among men (82%), and those aged over 45 years (84.8%). The dominant cancer type was squamous cell carcinoma of the external lower lip (predominantly in men). We recorded high rates of chronic solar exposure, and tobacco and alcohol drinking habits in patients with squamous cell carcinoma.
Individuals aged over 45 years are at higher risk for lip cancer. The high association of the examined risk factors with the rate of squamous cell carcinoma confirms their role in the development of this type of tumor.
唇癌是口腔颌面部最常见的肿瘤。在过去十年中，意大利人群中唇癌的发病率一直很高。
本回顾性研究分析了 2000 年至 2010 年间来我院就诊的唇癌患者的流行病学数据和危险因素。本研究的统计分析采用学生 t 检验和卡方检验。
在 540 例患者中，大多数为男性（82%）和 45 岁以上人群（84.8%）。主要癌症类型为外下唇鳞状细胞癌（主要见于男性）。我们记录了患有鳞状细胞癌的患者中慢性太阳暴露、烟草和饮酒习惯的高发率。
45 岁以上人群患唇癌的风险更高。所检查的危险因素与鳞状细胞癌发生率之间的高度关联证实了它们在这种类型肿瘤发展中的作用。
