Cattermole Giles N, Leung P Y Mia, Ho Grace Y L, Lau Peach W S, Chan Cangel P Y, Chan Stewart S W, Smith Brendan E, Graham Colin A, Rainer Timothy H
Emergency Department, Centre Hospitalier Universitaire de Kigali, Kigali, Rwanda
Department of Medicine, Austin/Northern Health, Melbourne, Australia.
Physiol Rep. 2017 Mar;5(6). doi: 10.14814/phy2.13195.
The ultrasonic cardiac output monitor (USCOM) is a noninvasive transcutaneous continuous wave Doppler method for assessing hemodynamics. There are no published reference ranges for normal values in adults (aged 18-60 years) for this device. This study aimed to (1) measure cardiovascular indices using USCOM in healthy adults aged 18-60 years; (2) combine these data with those for healthy children (aged 0-12), adolescents (aged 12-18), and the elderly (aged over 60) from our previously published studies in order to present normal ranges for all ages, and (3) establish normal ranges of USCOM-derived variables according to both weight and age. This was a population-based cross-sectional observational study of healthy Chinese subjects aged 0.5-89 years in Hong Kong. USCOM scans were performed on all subjects, to produce measurements including stroke volume, cardiac output, and systemic vascular resistance. Data from previously published studies (children, adolescents, and the elderly) were included. Normal ranges were defined as lying between the 2.5th and 97.5th percentiles. A total of 2218 subjects were studied (mean age = 16.4, range = 0.5-89; 52% male). From previous studies, 1197 children (aged 0-12, 55% male), 590 adolescents (aged 12-18, 49% male), and 77 elderly (aged 60-89, 55% male) were included. New data were collected from 354 adults aged 18-60 (47% male). Normal ranges are presented according to age and weight. We present comprehensive normal ranges for hemodynamic parameters obtained with USCOM in healthy subjects of all ages from infancy to the elderly.
超声心输出量监测仪(USCOM)是一种用于评估血流动力学的非侵入性经皮连续波多普勒方法。目前尚无关于该设备在18至60岁成年人中的正常参考范围的公开报道。本研究旨在:(1)使用USCOM测量18至60岁健康成年人的心血管指标;(2)将这些数据与我们之前发表的关于健康儿童(0至12岁)、青少年(12至18岁)和老年人(60岁以上)的研究数据相结合,以给出所有年龄段的正常范围;(3)根据体重和年龄建立USCOM衍生变量的正常范围。这是一项基于人群的横断面观察性研究,研究对象为香港年龄在0.5至89岁的健康中国受试者。对所有受试者进行USCOM扫描,以得出包括每搏输出量、心输出量和体循环血管阻力在内的测量值。纳入了之前发表的研究(儿童、青少年和老年人)的数据。正常范围定义为第2.5百分位数和第97.5百分位数之间。共研究了2218名受试者(平均年龄=16.4岁,范围=0.5至89岁;52%为男性)。从之前的研究中,纳入了1197名儿童(0至12岁,55%为男性)、590名青少年(12至18岁,49%为男性)和77名老年人(60至89岁,55%为男性)。从354名18至60岁的成年人(47%为男性)中收集了新数据。根据年龄和体重给出了正常范围。我们给出了从婴儿期到老年人所有年龄段健康受试者使用USCOM获得的血流动力学参数的综合正常范围。