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[先天性巨细胞病毒感染并导致致命后果]

[Congenital cytomegalovirus infection with fatal outcome].

作者信息

Jahn G, Pohl W, Plachter B, Hintzenstern J

机构信息

Institut für Klinische und Molekulare Virologie der Universität Erlangen-Nürnberg.

出版信息

Dtsch Med Wochenschr. 1988 Mar 18;113(11):424-7. doi: 10.1055/s-2008-1067656.

DOI:10.1055/s-2008-1067656
PMID:2832140
Abstract

A 34-year-old woman had an essentially uneventful pregnancy until membrane rupture in the 30th week of pregnancy. She developed severe eclampsia necessitating delivery by section in the 36th week. The child was asphyxic at birth with petechial haemorrhages and hepatosplenomegaly, suggesting cytomegalovirus infection (CMV). He died on the fourth day. Virus could not be isolated from maternal urine, cervical smear and placental tissue, but was demonstrated in the child's urine and post-mortem in lung and liver tissue. The ELISA test on the child's serum was positive for CMV-specific IgM antibodies.

摘要

一名34岁女性在妊娠期间基本顺利,直到妊娠第30周胎膜破裂。她发展为严重子痫,在第36周时需要剖宫产。孩子出生时窒息,有瘀点出血和肝脾肿大,提示巨细胞病毒(CMV)感染。他在第四天死亡。病毒无法从母亲尿液、宫颈涂片和胎盘组织中分离出来,但在孩子的尿液以及死后的肺和肝组织中被检测到。对孩子血清进行的ELISA检测显示CMV特异性IgM抗体呈阳性。

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