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一名33岁患有严重动脉低血压的女性出现无痛性双侧视力丧失。

Painless bilateral visual loss in a 33-year-old woman with severe arterial hypotension.

作者信息

Subirà Olaia, Muñoz Silvia, Sánchez Juan José, Puyalto Paloma, Lee Andrew G

机构信息

Department of Ophthalmology, Hospital Universitari de Bellvitge, Barcelona, Spain.

Department of Ophthalmology, Hospital Universitari de Bellvitge, Barcelona, Spain.

出版信息

Surv Ophthalmol. 2018 Jan-Feb;63(1):125-131. doi: 10.1016/j.survophthal.2017.03.001. Epub 2017 Mar 16.

DOI:10.1016/j.survophthal.2017.03.001
PMID:28322870
Abstract

A 32-year-old woman experienced dizziness and headache for 5 months. She also complained of painless, progressive bilateral visual loss for several weeks. Before developing the initial symptoms, she had an uncomplicated pregnancy except for dizziness and systemic hypotension during the first term. Fundus examination disclosed prominent retinal arteries as well diffuse microaneurysms, widespread intraretinal hemorrhages, and hyperemic optic disks. Brain magnetic resonance imaging revealed multiple supratentorial white-matter lesions suggestive of ischemic strokes. Initially, she had severe systemic hypotension (41/17 mm Hg). When reassessed, blood pressure was normal in the lower limbs, but there was severe hypotension in the upper limbs. An angio-computed tomography of the supraortic trunks showed occlusion of both primitive carotid arteries, both subclavian arteries and the right axillary and humeral arteries. Based on these findings, the diagnosis of Takayasu type-I arteritis with ischemic retinopathy and cerebrovascular disease was established. Bilateral retinal panphotocoagulation and aorta to right carotid bypass were performed because of the severity of the ischemic lesions.

摘要

一名32岁女性经历了5个月的头晕和头痛。她还诉说了数周无痛性、进行性双侧视力丧失。在出现初始症状之前,她孕期正常,仅在孕早期有头晕和全身低血压。眼底检查发现视网膜动脉显著增粗,并有弥漫性微动脉瘤、广泛的视网膜内出血以及视盘充血。脑部磁共振成像显示幕上多个白质病变,提示缺血性卒中。最初,她有严重的全身低血压(41/17毫米汞柱)。再次评估时,下肢血压正常,但上肢有严重低血压。主动脉弓上血管的血管计算机断层扫描显示双侧原始颈动脉、双侧锁骨下动脉以及右侧腋动脉和肱动脉闭塞。基于这些发现,确诊为I型大动脉炎伴缺血性视网膜病变和脑血管疾病。由于缺血性病变严重,进行了双侧视网膜全视网膜光凝和主动脉至右颈动脉搭桥手术。

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Surv Ophthalmol. 2018 Jan-Feb;63(1):125-131. doi: 10.1016/j.survophthal.2017.03.001. Epub 2017 Mar 16.
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引用本文的文献

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Posterior segment manifestations of Takayasu arteritis: A narrative review.Takayasu 动脉炎的后节段表现:叙述性综述。
Indian J Ophthalmol. 2024 May 1;72(5):637-647. doi: 10.4103/IJO.IJO_1346_23. Epub 2024 Apr 22.
2
Ocular Manifestations of Takayasu's Arteritis-A Case-Based Systematic Review and Meta-Analysis.高安动脉炎的眼部表现——基于病例的系统评价与荟萃分析
J Clin Med. 2023 May 29;12(11):3745. doi: 10.3390/jcm12113745.
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Therapeutic Management of Ocular Ischemia in Takayasu's Arteritis: A Case-Based Systematic Review.
Takayasu 动脉炎致眼部缺血的治疗管理:基于病例的系统评价。
Front Immunol. 2022 Jan 14;12:791278. doi: 10.3389/fimmu.2021.791278. eCollection 2021.