Muñoz Ociel, Zamorano Pedro, Garcia Olga, Bastías José Miguel
Food Science and Technology Institute (ICYTAL), Faculty of Agricultural Sciences, Universidad Austral de Chile, Campus Isla Teja s/n, Valdivia, Chile.
Food Science and Technology Institute (ICYTAL), Faculty of Agricultural Sciences, Universidad Austral de Chile, Campus Isla Teja s/n, Valdivia, Chile.
Food Chem Toxicol. 2017 Nov;109(Pt 2):1125-1134. doi: 10.1016/j.fct.2017.03.027. Epub 2017 Mar 16.
This study was designed to estimate the dietary intake of total arsenic, inorganic arsenic, cadmium, mercury, sodium, and potassium by the general adult population (aged 18-65) of Valdivia, Chile. Calculations were based on a 24-h dietary recall survey. The highest dietary intake of t-As (73.0 μg/day), i-As (20.0 μg/day), Cd (18.0 μg/day), Hg (5.8 μg/day), Na (3112.8 mg/day), and K (2077.5 mg/day) were for 70-kg adults. Estimating carcinogenic risk (CR > 4 × 10) due to exposure to i-As indicated that consumers remain at low risk for cancer. The cumulative health risk was evaluated by summing the target hazard quotient of cadmium (0.26) mercury (0.27) and inorganic arsenic (0.96); this calculation allows us to express the total target hazard quotient as 1.50 where a value > 1 indicates that there is a potential health risk for the population. Total intake of Cd and Hg were therefore within the limits estimated as being safe whereas Na and K intake for the Valdivia population did not follow the recommended values established by the World Health Organization (WHO). The Na intake exceeded the daily recommended intake while K intake was lower than the daily recommended intake. This indicates a health risk for the Valdivia population.
本研究旨在估算智利瓦尔迪维亚普通成年人群(18 - 65岁)的总砷、无机砷、镉、汞、钠和钾的膳食摄入量。计算基于24小时膳食回顾调查。体重70千克的成年人,总砷(73.0微克/天)、无机砷(20.0微克/天)、镉(18.0微克/天)、汞(5.8微克/天)、钠(3112.8毫克/天)和钾(2077.5毫克/天)的膳食摄入量最高。对因接触无机砷导致的致癌风险(CR > 4×10)进行估算表明,消费者的癌症风险仍然较低。通过将镉(0.26)、汞(0.27)和无机砷(0.96)的目标危害商数相加来评估累积健康风险;该计算使我们能够将总目标危害商数表示为1.50,其中大于1的值表明人群存在潜在健康风险。因此,镉和汞的总摄入量在估计的安全限值内,而瓦尔迪维亚人群的钠和钾摄入量未遵循世界卫生组织(WHO)制定的推荐值。钠摄入量超过每日推荐摄入量,而钾摄入量低于每日推荐摄入量。这表明瓦尔迪维亚人群存在健康风险。