Kaplan Ince Olcay, Ince Muharrem, Onal Ali
Department of Gastronomy and Culinary Arts, Faculty of Fine Arts, Design and Architecture, Munzur University, 62000 Tunceli, Turkey.
Department of Food Processes, Tunceli Vocational School, Munzur University, 62000 Tunceli, Turkey.
J Food Sci Technol. 2022 Oct;59(10):4005-4015. doi: 10.1007/s13197-022-05441-0. Epub 2022 Apr 1.
Risk assessment of cadmium (Cd) for human health play a key role because of toxic effect. Researchers are undergoing constant development for modelling approaches to make a risk assessment. It was carried out a central composite design combining with response surface modeling to optimize and modeling of Cd ions in this study. Also, this study was performed to provide information about possible risk associated with alcoholic beverage consumption. Some independent process parameters including contact time and pH were chosen for optimization. Under optimal parameters, 142.9 mg g was determined as Cd ions removal effectiveness. Significance independent parameters and their interactions were checked using analysis of variance. These results were verified by correlation coefficients (R = 0.9967) of the statistical prediction. Estimated daily intake (EDI) and target hazard quotients (THQ) were calculated, to assess health risk. The Cd ions EDI values (µg/day/person) were less than the recommended dietary allowance values and also, its THQ value was less than 1, also. When the obtained results compared with the levels set by regulatory authorities, the studied alcoholic beverages consumption do not pose a toxicological risk.
由于镉（Cd）的毒性作用，对人体健康进行风险评估至关重要。研究人员不断开发建模方法以进行风险评估。本研究采用中心复合设计结合响应面建模对镉离子进行优化和建模。此外，本研究旨在提供与酒精饮料消费相关的潜在风险信息。选择了一些独立的工艺参数，包括接触时间和pH值进行优化。在最佳参数下，镉离子去除效率确定为142.9 mg/g。使用方差分析检查显著的独立参数及其相互作用。这些结果通过统计预测的相关系数（R = 0.9967）得到验证。计算估计每日摄入量（EDI）和目标危害商（THQ）以评估健康风险。镉离子的EDI值（μg/天/人）低于推荐膳食摄入量值，其THQ值也小于1。当将所得结果与监管机构设定的水平进行比较时，所研究的酒精饮料消费不会构成毒理学风险。
