光感受器细胞损伤始于 Vogt-Koyanagi-Harada 病的早期阶段。
Photoreceptor Cell Injury Starts in the Initial Stage of Vogt-Koyanagi-Harada Disease.
机构信息
a Department of Ophthalmology , Peking University First Hospital, Key Laboratory of Vision Loss and Restoration, Ministry of Education , Beijing , China.
出版信息
Ocul Immunol Inflamm. 2018;26(6):934-942. doi: 10.1080/09273948.2017.1285035. Epub 2017 Mar 21.
PURPOSE
To demonstrate photoreceptor cell injury in Vogt-Koyanagi-Harada (VKH) disease.
METHODS
The SD-OCT and FAF tests of 16 patients diagnosed with VKH disease that was followed up from the initial stage to the convalescent stage were reviewed.
RESULTS
In the initial stage of VKH disease, there was hyperautofluerescence around the macular edema. In the convalescent stage of VKH disease, loss of photoreceptor and injury of RPE have been detected by OCT scan at the same area, which was corresponded with the abnormalities in FAF.
CONCLUSIONS
The VKH disease causes photoreceptor injury starting in the initial stage of the disease.
目的
展示 Vogt-小柳-原田（Vogt-Koyanagi-Harada，VKH）病中的光感受器细胞损伤。
方法
对 16 例 VKH 病患者的 SD-OCT 和 FAF 检查结果进行回顾性分析，这些患者均从疾病的初始阶段随访到恢复期。
结果
在 VKH 病的初始阶段，黄斑水肿周围有高自发荧光。在 VKH 病的恢复期，OCT 扫描在同一区域检测到光感受器丧失和 RPE 损伤，与 FAF 的异常相对应。
结论
VKH 病在疾病的初始阶段就引起光感受器损伤。
Zotero 插件