Ellwanger Joel Henrique, Chies José Artur Bogo
Laboratório de Imunogenética, Programa de Pós-Graduação em Genética e Biologia Molecular, Departamento de Genética, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Rev Soc Bras Med Trop. 2017 Jan-Feb;50(1):3-8. doi: 10.1590/0037-8682-0330-2016.
Emerging infectious diseases are a global threat. In countries like Brazil, where biodiversity is high and public health conditions in terms of infrastructure and medical care are often precarious, emerging diseases are particularly worrisome. The lack of monitoring strategies to identify pathogens with the potential to cause outbreaks or epidemics is another problem in Brazil and other developing countries. In this article, we present the history of the Sabiá virus (SABV), a pathogen that was described in the 1990s in Brazil. Several aspects of the biology and ecology of the SABV remain unknown. The SABV has the potential to cause hemorrhagic fever in humans. To date, four cases of human infections have been reported worldwide; two were naturally acquired (both in Brazil), whereas the other two were linked to occupational exposure in the laboratory environment (one in Brazil and one in the USA). In this review, we summarize the basic biological and ecological characteristics of the SABV. This is the first work to gather all available data on the historical aspects involving the cases of SABV infection along with an update on its characteristic features.
新发传染病是一种全球威胁。在巴西这样生物多样性高且基础设施和医疗保健方面的公共卫生条件往往不稳定的国家，新发疾病尤其令人担忧。在巴西和其他发展中国家，另一个问题是缺乏识别有可能引发疫情或流行病的病原体的监测策略。在本文中，我们介绍了萨比亚病毒（SABV）——一种20世纪90年代在巴西被发现的病原体——的历史。SABV生物学和生态学的几个方面仍然未知。SABV有可能导致人类出血热。迄今为止，全球已报告4例人类感染病例；其中2例是自然感染（均在巴西），另外2例与实验室环境中的职业暴露有关（1例在巴西，1例在美国）。在这篇综述中，我们总结了SABV的基本生物学和生态学特征。这是第一项收集所有关于SABV感染病例历史方面的可用数据以及其特征最新情况的研究。
