动物实验中疼痛和镇痛的副作用。
Side effects of pain and analgesia in animal experimentation.
机构信息
Division of Surgical Research, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
出版信息
Lab Anim (NY). 2017 Mar 22;46(4):123-128. doi: 10.1038/laban.1216.
PMID:28328895
Abstract
This review highlights selected effects of untreated pain and of widely used analgesics such as opioids, non-steroid anti-inflammatory drugs and antipyretics, to illustrate the relevance of carefully planned, appropriate and controlled analgesia for greater reproducibility in animal experiments involving laboratory rodents.
摘要
这篇综述重点介绍了未治疗疼痛和广泛使用的镇痛药（如阿片类药物、非甾体抗炎药和退烧药）的一些选定影响，以说明在涉及实验室啮齿动物的动物实验中，精心计划、适当和控制的镇痛的相关性，以提高实验结果的可重复性。
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