Mills Adam C, Badour Christal L, Korte Kristina J, Killeen Therese K, Henschel Aisling V, Back Sudie E
Department of Psychiatry and Behavioral Sciences, Addictions Sciences Division, Medical University of South Carolina, Charleston, South Carolina, USA.
Ralph H. Johnson VA Medical Center, Mental Health Service Line, Charleston, South Carolina, USA.
J Trauma Stress. 2017 Apr;30(2):166-172. doi: 10.1002/jts.22175. Epub 2017 Mar 22.
Efforts to improve the efficiency of prolonged exposure (PE) therapy for posttraumatic stress disorder (PTSD) have demonstrated that reducing the length of imaginal exposures does not negatively affect treatment outcome. A recent adaptation of PE, called Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure [COPE], integrates substance use disorder treatment with PE in the same timeframe (twelve 90-minute sessions, 8 of which include imaginal exposure). The current study, which represents a subanalysis of a larger randomized controlled trial, examined how the length of imaginal exposures (nonrandomized and measured continually) related to PTSD, substance use, and depression in a sample of military veterans (N = 31) who completed the COPE treatment. Participants completed an average of 11.5 of the 12 therapy sessions and 7.2 of the 8 imaginal exposures during treatment. Results of 3 linear mixed models indicate that PTSD, substance use, and depressive symptoms all improved over the course of treatment (ps < .001; η ranged between .17 and .40), and that the length of imaginal exposures did not significantly interact with any outcome. Although preliminary, the findings suggest that it may be feasible to shorten imaginal exposures without mitigating treatment gains. Implications for treatment are discussed.
为提高创伤后应激障碍(PTSD)延长暴露疗法(PE)的效率所做的努力表明,缩短想象暴露的时长并不会对治疗效果产生负面影响。PE疗法最近的一种改编形式,即使用延长暴露同时治疗PTSD和物质使用障碍[COPE],在同一时间段内(共十二次90分钟的疗程,其中八次包括想象暴露)将物质使用障碍治疗与PE疗法相结合。本研究是一项更大规模随机对照试验的子分析,它考察了在完成COPE治疗的退伍军人样本(N = 31)中,想象暴露的时长(非随机且持续测量)与PTSD、物质使用及抑郁之间的关系。参与者在治疗期间平均完成了12次治疗疗程中的11.5次,以及8次想象暴露中的7.2次。三个线性混合模型的结果表明,在整个治疗过程中,PTSD、物质使用及抑郁症状均有所改善(p值均小于0.001;效应量η在0.17至0.40之间),且想象暴露的时长与任何结果均无显著交互作用。尽管这些发现尚属初步,但它们表明缩短想象暴露时长而不降低治疗效果可能是可行的。文中还讨论了对治疗的启示。