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一名HIV阴性汉族男性的经典型卡波西肉瘤:病例报告

Classic Kaposi sarcoma in an HIV-negative Han Chinese man: a case report.

作者信息

Mitre Victoria, Applebaum Danielle S, Potenziani Silvia, Hsu Sylvia

机构信息

Baylor College of Medicine, Department of Dermatology.

出版信息

Dermatol Online J. 2017 Jan 15;23(1):13030/qt9dk0n62k.

Abstract

Kaposi sarcoma (KS) is a multifocal angioproliferativetumor of endothelial origin. Despite nearly identicalclinical and histopathologic presentations, KS isclassified into four distinct varieties: classic/sporadic,AIDS-associated, African/endemic, and iatrogenic. Allsubtypes are invariably linked to human herpesvirus-8(HHV-8) and show a male predilection. Classic Kaposisarcoma is exceedingly rare in the Asian populationand its incidence varies by region and ethnic grouppredominance. A study in the Xinjiang region of Chinafound that only 1% of classic KS cases occurred inpatients belonging to the Han Chinese ethnic group,which formulates 84% of the Taiwanese population.Therefore, classic KS is extremely rare in Taiwan, withvery few reports describing the manifestations ofdisease in this population. We report a case of animmunocompetent 68-year-old HIV-negative HanChinese man born and raised in Taiwan with classicKaposi sarcoma on his trunk and extremities.

摘要

卡波西肉瘤(KS)是一种起源于内皮细胞的多灶性血管增殖性肿瘤。尽管临床和组织病理学表现几乎相同,但KS可分为四种不同类型:经典/散发性、艾滋病相关型、非洲/地方性和医源性。所有亚型均与人类疱疹病毒8型(HHV-8)相关,且男性更为常见。经典卡波西肉瘤在亚洲人群中极为罕见,其发病率因地区和种族优势而异。中国新疆地区的一项研究发现,经典KS病例中只有1%发生在占台湾人口84%的汉族患者中。因此,经典KS在台湾极为罕见,很少有报道描述该人群的疾病表现。我们报告一例免疫功能正常、68岁、HIV阴性、在台湾出生并长大的汉族男性,其躯干和四肢患有经典卡波西肉瘤。

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