Malviya Neeta, Cyrus Nika, Vandergriff Travis, Mauskar Melissa
Department of Dermatology, University of Texas Southwestern Medical Center.
Dermatol Online J. 2017 Feb 15;23(2):13030/qt5zw8d8vs.
Fixed drug eruptions (FDE) comprise 10 percent of alladverse cutaneous drug reactions and generalizedbullous fixed drug eruptions (GBFDE) are a raresubset of FDEs. We present a patient with severeGBFDE caused by ibuprofen successfully treated withcyclosporine. Further work is needed to determine ifcyclosporine can be an effective therapy for GBFDE.
固定性药疹（FDE）占所有药物性皮肤不良反应的10%，而泛发性大疱性固定性药疹（GBFDE）是FDE的一种罕见亚型。我们报告1例由布洛芬引起的严重GBFDE患者，经环孢素成功治疗。还需要进一步研究以确定环孢素是否可作为GBFDE的有效治疗方法。
