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基于LSO的正电子发射断层扫描仪中Lu本底的表征

Characterization of Lu background in LSO-based PET scanners.

作者信息

Conti Maurizio, Eriksson Lars, Rothfuss Harold, Sjoeholm Therese, Townsend David, Rosenqvist Göran, Carlier Thomas

机构信息

Siemens Healthcare Molecular Imaging, Knoxville, United States of America.

出版信息

Phys Med Biol. 2017 May 7;62(9):3700-3711. doi: 10.1088/1361-6560/aa68ca. Epub 2017 Mar 23.

Abstract

LSO and LYSO are today the most common scintillators used in positron emission tomography. Lutetium contains traces of Lu, a radioactive isotope that decays β with a cascade of γ photons in coincidence. Therefore, Lutetium-based scintillators are characterized by a small natural radiation background. In this paper, we investigate and characterize the Lu radiation background via experiments performed on LSO-based PET scanners. LSO background was measured at different energy windows and different time coincidence windows, and by using shields to alter the original spectrum. The effect of radiation background in particularly count-starved applications, such as Y imaging, is analysed and discussed. Depending on the size of the PET scanner, between 500 and 1000 total random counts per second and between 3 and 5 total true coincidences per second were measured in standard coincidence mode. The LSO background counts in a Siemens mCT in the standard PET energy and time windows are in general negligible in terms of trues, and are comparable to that measured in a BGO scanner of similar size.

摘要

LSO和LYSO是目前正电子发射断层扫描中最常用的闪烁体。镥含有痕量的镥-176,这是一种放射性同位素,它通过一系列符合的γ光子进行β衰变。因此,基于镥的闪烁体具有天然辐射背景小的特点。在本文中,我们通过在基于LSO的正电子发射断层扫描仪上进行的实验来研究和表征镥的辐射背景。在不同的能量窗口和不同的时间符合窗口下测量LSO背景,并使用屏蔽来改变原始能谱。分析和讨论了辐射背景在特别是计数匮乏的应用(如Y成像)中的影响。根据正电子发射断层扫描仪的大小,在标准符合模式下,每秒测量到的总随机计数在500到1000之间,每秒的总真符合数在3到5之间。在标准正电子发射断层能量和时间窗口下,西门子mCT中的LSO背景计数在真符合方面通常可以忽略不计,并且与在类似大小的BGO扫描仪中测量到的计数相当。

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