Umemura Kazuo, Izumi Katsuki, Oura Shusuke
Biophysics Section, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku, Tokyo 162-8601, Japan.
Nanomaterials (Basel). 2016 Oct 8;6(10):180. doi: 10.3390/nano6100180.
Hybrids of DNA and carbon nanotubes (CNTs) are promising nanobioconjugates for nanobiosensors, carriers for drug delivery, and other biological applications. In this review, nanoscopic characterization of DNA-CNT hybrids, in particular, characterization by scanning probe microscopy (SPM), is summarized. In many studies, topographical imaging by atomic force microscopy has been performed. However, some researchers have demonstrated advanced SPM operations in order to maximize its unique and valuable functions. Such sophisticated approaches are attractive and will have a significant impact on future studies of DNA-CNT hybrids.
DNA与碳纳米管（CNT）的杂化物是用于纳米生物传感器、药物递送载体及其他生物应用的很有前景的纳米生物共轭物。在这篇综述中，总结了DNA-CNT杂化物的纳米级表征，特别是通过扫描探针显微镜（SPM）进行的表征。在许多研究中，已经利用原子力显微镜进行了形貌成像。然而，一些研究人员展示了先进的SPM操作，以最大限度地发挥其独特且有价值的功能。这种复杂的方法很有吸引力，将对未来DNA-CNT杂化物的研究产生重大影响。
