Govindhan Maduraiveeran, Liu Zhonggang, Chen Aicheng
Department of Chemistry, Lakehead University, 955 Oliver Road, Thunder Bay, ON P7B 5E1, Canada.
Nanomaterials (Basel). 2016 Nov 14;6(11):211. doi: 10.3390/nano6110211.
The extensive physiological and regulatory roles of nitric oxide (NO) have spurred the development of NO sensors, which are of critical importance in neuroscience and various medical applications. The development of electrochemical NO sensors is of significant importance, and has garnered a tremendous amount of attention due to their high sensitivity and selectivity, rapid response, low cost, miniaturization, and the possibility of real-time monitoring. Nanostructured platinum (Pt)-based materials have attracted considerable interest regarding their use in the design of electrochemical sensors for the detection of NO, due to their unique properties and the potential for new and innovative applications. This review focuses primarily on advances and insights into the utilization of nanostructured Pt-based electrode materials, such as nanoporous Pt, Pt and PtAu nanoparticles, PtAu nanoparticle/reduced graphene oxide (rGO), and PtW nanoparticle/rGO-ionic liquid (IL) nanocomposites, for the detection of NO. The design, fabrication, characterization, and integration of electrochemical NO sensing performance, selectivity, and durability are addressed. The attractive electrochemical properties of Pt-based nanomaterials have great potential for increasing the competitiveness of these new sensors and open up new opportunities in the creation of novel NO-sensing technologies for biological and medical applications.
一氧化氮（NO）广泛的生理和调节作用推动了NO传感器的发展，这些传感器在神经科学和各种医学应用中至关重要。电化学NO传感器的发展具有重要意义，因其高灵敏度、高选择性、快速响应、低成本、小型化以及实时监测的可能性而备受关注。基于纳米结构的铂（Pt）材料因其独特的性能以及新的创新应用潜力，在用于检测NO的电化学传感器设计中引起了相当大的兴趣。本综述主要关注纳米结构的Pt基电极材料，如纳米多孔Pt、Pt和PtAu纳米颗粒、PtAu纳米颗粒/还原氧化石墨烯（rGO）以及PtW纳米颗粒/rGO-离子液体（IL）纳米复合材料在检测NO方面的进展和见解。文中探讨了电化学NO传感性能、选择性和耐久性的设计、制备、表征及整合。基于Pt的纳米材料具有吸引人的电化学特性，在提高这些新型传感器的竞争力方面具有巨大潜力，并为生物和医学应用中新型NO传感技术的创建开辟了新机遇。
