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牛初乳乳清蛋白水解物在体外抑制细胞DNA损伤和低密度脂蛋白氧化。

Bovine Colostrum Whey Protein Hydrolysate Inhibits Cell DNA Damage and LDL Oxidation In Vitro.

作者信息

Chiang Shu-Hua, Wang Shiu-Yu, Chang Chi-Yue, Chen Chih-Wei

机构信息

Department of Health and Creative Vegetarian Science, FoGuang University, No. 160, Linwei Rd., Jiaosi, Yilan County 26247, Taiwan.

Department of Biological Science and Technology, I-Shou University, Kaohsiung 84001, Taiwan.

出版信息

Molecules. 2017 Mar 13;22(3):456. doi: 10.3390/molecules22030456.

DOI:10.3390/molecules22030456
PMID:28335407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6155289/
Abstract

Whey protein isolated from bovine colostrums collected on the second day postpartum was two-stage hydrolyzed by alcalase and flavourzyme [...].

摘要

从产后第二天收集的牛初乳中分离出的乳清蛋白，先后用碱性蛋白酶和风味酶进行两步水解处理[……]

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/2de3f85bc07d/molecules-22-00456-g005a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/ca86e66b4600/molecules-22-00456-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/a6ffaa4e18ac/molecules-22-00456-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/1aec8caedcae/molecules-22-00456-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/5b0b73822b8f/molecules-22-00456-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/2de3f85bc07d/molecules-22-00456-g005a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/ca86e66b4600/molecules-22-00456-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/a6ffaa4e18ac/molecules-22-00456-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/1aec8caedcae/molecules-22-00456-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/5b0b73822b8f/molecules-22-00456-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4516/6155289/2de3f85bc07d/molecules-22-00456-g005a.jpg

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本文引用的文献

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2
The Inhibition Effect of Cell DNA Oxidative Damage and LDL Oxidation by Bovine Colostrums.牛初乳对细胞DNA氧化损伤和低密度脂蛋白氧化的抑制作用
Molecules. 2016 Oct 21;21(10):1378. doi: 10.3390/molecules21101378.
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Green tea catechins prevent low-density lipoprotein oxidation via their accumulation in low-density lipoprotein particles in humans.
牛奶摄入与全因死亡率和心血管结局的关联：基于英国生物库的大型人群队列研究。
J Transl Med. 2023 Feb 18;21(1):130. doi: 10.1186/s12967-023-03980-4.
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The Bioactive Compound Contents and Potential Protective Effects of Royal Jelly Protein Hydrolysates against DNA Oxidative Damage and LDL Oxidation.蜂王浆蛋白水解物的生物活性成分及其对DNA氧化损伤和低密度脂蛋白氧化的潜在保护作用。
Antioxidants (Basel). 2021 Apr 9;10(4):580. doi: 10.3390/antiox10040580.
绿茶儿茶素通过在人体低密度脂蛋白颗粒中的积聚来防止低密度脂蛋白氧化。
Nutr Res. 2016 Jan;36(1):16-23. doi: 10.1016/j.nutres.2015.10.012. Epub 2015 Nov 3.
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Whey protein inhibits iron overload-induced oxidative stress in rats.乳清蛋白可抑制大鼠体内铁过载诱导的氧化应激。
J Nutr Sci Vitaminol (Tokyo). 2013;59(3):198-205. doi: 10.3177/jnsv.59.198.
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In situ DNA oxidative damage by electrochemically generated hydroxyl free radicals on a boron-doped diamond electrode.电化学产生的羟基自由基在掺硼金刚石电极上引起的 DNA 原位氧化损伤。
Langmuir. 2012 Mar 13;28(10):4896-901. doi: 10.1021/la300070x. Epub 2012 Mar 1.
6
The LDL modification hypothesis of atherogenesis: an update.动脉粥样硬化发生的低密度脂蛋白修饰假说：最新进展。
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7
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