Department of Pediatrics, King George's Medical University, Lucknow, Uttar Pradesh, 226003, India.
Department of Radiodiagnosis, King George's Medical University, Lucknow, Uttar Pradesh, India.
Indian J Pediatr. 2017 Jul;84(7):499-504. doi: 10.1007/s12098-017-2333-1. Epub 2017 Mar 24.
To evaluate the accuracy of lung ultrasound (LUS) in comparison to chest roentgenogram (CXR) in hospitalised children with community-acquired pneumonia (CAP).
This study was a hospital based prospective observational study, conducted between January 2014 and December 2014. Hospitalised children aged 2 to 59 mo with community-acquired pneumonia were included in the study. The informed written consent was taken from parents (or legal guardian) before recruitment. Children with suspected or proven asthma, cystic fibrosis, congenital heart disease, immunodeficiency, malignancy and hemodynamic unstability were excluded. CXR, posterio-anterior view, and LUS were done within 24 h of the hospitalisation.
Of 176 consecutively hospitalised cases of CAP, 118 were recruited after screening (65, 55.1% boys; mean age in months ± SD, 26.22 ± 19.60). Abnormal CXR were found in 101 (85.6%) and abnormal LUS in 105 (89%) children. In radiologically proven CAP, LUS was positive in 99/101(98.01%) while among radiologically normal, LUS was abnormal in 6/17 (35.3%). LUS has high sensitivity (98.02%) and reasonable specificity (64.71%) for diagnosing radiologically proven CAP. In diagnosing the specific radiological type of CAP, there was very good concordance (Quadratic Weighted Cohen's Kappa =0.7) between CXR and LUS. Similarly, the authors also found excellent concordance between CXR and LUS (Linear Weighted Cohen's Kappa =0.9) for diagnosis of pleural effusion.
LUS can be considered to be used first before radiography in children with suspected CAP. This will reduce the exposure of radiation.
评估肺部超声(LUS)与胸部 X 线(CXR)在社区获得性肺炎(CAP)住院患儿中的准确性。
这是一项 2014 年 1 月至 12 月在医院进行的前瞻性观察研究。纳入患有社区获得性肺炎的 2 至 59 月龄住院患儿。在招募前,征得患儿父母(或法定监护人)的知情书面同意。排除疑似或确诊哮喘、囊性纤维化、先天性心脏病、免疫缺陷、恶性肿瘤和血流动力学不稳定的患儿。入院后 24 小时内进行 CXR 后前位和 LUS。
在连续收治的 176 例 CAP 患儿中,经筛选后纳入 118 例(男 65 例,55.1%;平均月龄 ± 标准差为 26.22 ± 19.60 月)。101 例(85.6%)患儿 CXR 异常,105 例(89%)患儿 LUS 异常。在影像学确诊的 CAP 患儿中,LUS 阳性 99/101(98.01%),而在影像学正常的患儿中,LUS 异常 6/17(35.3%)。LUS 诊断影像学确诊 CAP 的敏感性(98.02%)较高,特异性(64.71%)尚可。在诊断 CAP 的具体影像学类型方面,CXR 与 LUS 之间具有很好的一致性(二次加权 Cohen's Kappa =0.7)。同样,作者还发现 CXR 与 LUS 之间在诊断胸腔积液方面具有极好的一致性(线性加权 Cohen's Kappa =0.9)。
在疑似 CAP 患儿中,LUS 可优先于 X 射线检查。这将减少射线暴露。