Cell Biology Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Cell. 2017 Mar 23;169(1):178-178.e1. doi: 10.1016/j.cell.2017.03.004.
Many cells localize mRNAs to discrete locations in the cytoplasm. Coupled to local translation, this process affords precise spatial and temporal control of protein function. This SnapShot provides an overview of the key events in subcellular mRNA localization and highlights recent progress in understanding how cytoskeletal motors orchestrate mRNA trafficking.
许多细胞将 mRNA 定位到细胞质中的离散位置。与局部翻译相结合，这个过程提供了对蛋白质功能的精确时空控制。这个 SnapShot 概述了细胞质 mRNA 定位的关键事件，并强调了最近在理解细胞骨架马达如何协调 mRNA 运输方面的进展。
