Lorenz D, Wolff H, Waclawiczek H
Chirurgische Klinik Ernst-Moritz-Arndt-Universität Greifswald.
Chirurg. 1988 Feb;59(2):90-5.
The original aims of pancreatic duct occlusion (PDO) were reduction of early complication rate after pancreas resection, influence on clinical symptoms by elimination of exocrine tissue and preservation of B-cell function in the remaining pancreas. As a result of a 3-years study in patients with chronic pancreatitis and carcinoma in whom a Whipple's operation with and without PDO had been carried out the evaluation of PDO was estimated. The PDO has a high value in pancreas head resections because of carcinoma. Similar is the importance in the reduction of clinical symptoms in patients with chronic pancreatitis. A protective effect could not be observed neither in patients with chronic pancreatitis nor with carcinoma. On the other hand there was no additional damage by PDO, as the comparison with patients without PDO has shown.
胰腺导管闭塞（PDO）最初的目的是降低胰腺切除术后的早期并发症发生率，通过消除外分泌组织来影响临床症状，并保留剩余胰腺中的B细胞功能。在对慢性胰腺炎和癌症患者进行了一项为期3年的研究后，对实施了或未实施PDO的惠普尔手术进行了评估。由于癌症，PDO在胰头切除术中具有很高的价值。在减轻慢性胰腺炎患者的临床症状方面也同样重要。无论是慢性胰腺炎患者还是癌症患者，均未观察到保护作用。另一方面，与未实施PDO的患者相比，PDO并未造成额外损害。
