[白细胞介素2受体在体内爱泼斯坦-巴尔病毒转化的B淋巴细胞中的表达]
[Expression of interleukin 2 receptors in in vivo Epstein-Barr virus transformed B lymphocytes].
作者信息
Becker H, Helmke K, Federlin K
机构信息
Universität Giessen, III. Medizinische Klinik und Poliklinik.
出版信息
Immun Infekt. 1988 Feb;16(1):21-2.
PMID:2834287
Abstract
Interleukin-2 (IL-2) enhances the proliferation of in vivo Epstein-Barr virus-(EBV)-transformed B-cells from patients with a present or past history of infectious mononucleosis. In contrast, there is less expression of functional IL-2 receptors on EBV-transformed B-cells from patients with rheumatoid arthritis. These results suggest differences in the involvement of B-cells in EBV-associated diseases.
摘要
白细胞介素-2（IL-2）可增强来自有现患或既往传染性单核细胞增多症病史患者的体内爱泼斯坦-巴尔病毒（EBV）转化的B细胞的增殖。相比之下，类风湿性关节炎患者的EBV转化B细胞上功能性IL-2受体的表达较少。这些结果表明B细胞在EBV相关疾病中的参与存在差异。
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