Rehabilitation Sciences Institute, Faculty of Medicine, University of Toronto, 550 University Avenue, Rm 11207, Toronto, ON, M5G 2A2, Canada.
Toronto Rehabilitation Institute-University Health Network, Toronto, ON, Canada.
Curr Neurol Neurosci Rep. 2017 Apr;17(4):38. doi: 10.1007/s11910-017-0744-z.
All living organisms that face a traumatic life event are susceptible to sleep-wake disturbances. Stress, which can result in trauma, evokes a high level of physiological arousal associated with sympathetic nervous system activation, during both sleep and wakefulness. Heredity, sex hormones, early losses, developmental factors and intra- and interpersonal conflicts, contribute to the level of baseline physiological arousal, producing either subclinical, clinical or complex clinical traits, acutely and at any time after exposure to a traumatic event. The risk of acute sleep-wake disturbances becoming disorders and syndromes depends on the type of traumatic event and all of the aforementioned factors. Taken together, with consideration for behavioural and environmental heterogeneity, in research, will aid identification and understanding of susceptibility factors in long-term sleep and wakefulness pathology after exposure to traumatic events.
所有面临创伤性生活事件的生物都容易出现睡眠-觉醒障碍。压力,它可能导致创伤,在睡眠和觉醒期间引起与交感神经系统激活相关的高水平生理唤醒。遗传、性激素、早期损失、发育因素以及内在和人际冲突,导致基线生理唤醒水平,产生亚临床、临床或复杂的临床特征,急性和在创伤事件暴露后的任何时间。急性睡眠-觉醒障碍发展为障碍和综合征的风险取决于创伤性事件的类型和所有上述因素。综合考虑行为和环境的异质性,在研究中,将有助于确定和理解创伤事件暴露后长期睡眠和觉醒病理的易感性因素。