Huh Hyu Jung, Baek Kwangyeol, Kwon Jae-Hyung, Jeong Jaeseung, Chae Jeong-Ho
a Department of Psychiatry , Seoul St. Mary's Hospital, The Catholic University of Korea, College of Medicine , Seoul , Republic of Korea.
b Department of Bio and Brain Engineering , Korea Advanced Institute of Science and Technology (KAIST) , Daejeon , Republic of Korea.
Cogn Neuropsychiatry. 2016 Nov;21(6):447-461. doi: 10.1080/13546805.2016.1230053. Epub 2016 Sep 22.
Although poor decision-making ultimately impairs quality of life in depression, few studies describe the clinical characteristics of patients suffering from dysfunctional decision-making. This study aims to delineate the effect of childhood trauma and other personality factors on risk-aversive and loss-aversive patterns of decision-making in patients with depression.
A total of 50 depressive patients completed surveys for the measurement of sociodemographic factors, trauma loads and other clinical characteristics, including depression, anxiety, and strategies for emotion regulation. Risk aversion and loss aversion were quantified using probability discounting task and a 50:50 gamble on monetary decision-making task under specified risks. Stepwise multiple regression analysis was performed to determine the factors, predicting risk aversion or loss aversion in depression.
Childhood trauma was the most prominent factor predicting loss aversion in patients with depressive disorders. Overall maladaptive emotion regulation strategies were associated with risk aversion.
Childhood trauma and specific strategies of emotion regulation contribute to risk or loss aversion in patients with depression. These findings may provide useful insight into elaborative evaluation and interventions to improve decision-making and quality of life in patients with depression.
尽管决策能力差最终会损害抑郁症患者的生活质量，但很少有研究描述存在功能失调决策的患者的临床特征。本研究旨在阐明童年创伤和其他人格因素对抑郁症患者风险厌恶和损失厌恶决策模式的影响。
共有50名抑郁症患者完成了关于社会人口统计学因素、创伤负荷及其他临床特征（包括抑郁、焦虑和情绪调节策略）的调查。使用概率折扣任务和在特定风险下关于货币决策任务的50:50赌博来量化风险厌恶和损失厌恶。进行逐步多元回归分析以确定预测抑郁症患者风险厌恶或损失厌恶的因素。
童年创伤是预测抑郁症患者损失厌恶的最突出因素。总体适应不良的情绪调节策略与风险厌恶相关。
童年创伤和特定的情绪调节策略导致抑郁症患者出现风险或损失厌恶。这些发现可能为深入评估和干预提供有用的见解，以改善抑郁症患者的决策能力和生活质量。
