Ganeshpurkar Aditya, Saluja Ajay K
Faculty of Pharmacy, Gujarat Technological University, Ahmedabad, Gujarat, India; Shri Ram Institute of Technology-Pharmacy, Jabalpur, Madhya Pradesh, India.
Faculty of Pharmacy, Gujarat Technological University, Ahmedabad, Gujarat, India; A.R. College of Pharmacy, Vallabh Vidyanagar, Gujarat, India.
Saudi Pharm J. 2017 Feb;25(2):149-164. doi: 10.1016/j.jsps.2016.04.025. Epub 2016 Apr 30.
The contemporary scientific community has presently recognized flavonoids to be a unique class of therapeutic molecules due to their diverse therapeutic properties. Of these, rutin, also known as vitamin P or rutoside, has been explored for a number of pharmacological effects. Tea leaves, apples, and many more possess rutin as one of the active constituents. Today, rutin has been observed for its nutraceutical effect. The present review highlights current information and health-promoting effects of rutin. Along with this, safety pharmacology issues and SAR of the same have also been discussed.
当代科学界目前已认识到黄酮类化合物因其多样的治疗特性而成为一类独特的治疗分子。其中,芦丁,也被称为维生素P或芸香苷,已被探索具有多种药理作用。茶叶、苹果等许多植物都含有芦丁作为活性成分之一。如今,芦丁已被观察到具有营养保健作用。本综述重点介绍了芦丁的当前信息及其促进健康的作用。同时,也讨论了其安全药理学问题和构效关系。