Athabasca University, Athabasca, Alberta, Canada.
University of Alberta, Edmonton, Alberta, Canada.
Sleep Health. 2017 Apr;3(2):102-106. doi: 10.1016/j.sleh.2016.12.002. Epub 2017 Jan 2.
Sleep is an important behavior for metabolic control and mental health in type 2 diabetes. The aim was to examine the relationship of objective estimates of sleep quantity and quality with health-related quality of life (HRQL) in adults with type 2 diabetes.
Participants completed a survey where HRQL was measured using the EQ-5D-5 L index score, and the SF-12 v2, which provides physical and mental composite summary (PCS and MCS) scores. Participants also wore wrist actigraphy (Actigraph GT3X+) during sleep to derive estimates of total sleep time (TST), sleep latency (SLAT), and sleep efficiency (SEFF) and wake after sleep onset (WASO). Adjusted multivariable linear regression models were used to examine the associations among actigraphy-derived sleep parameters with PCS, MCS, and EQ-5D-5 L index scores.
On average, participants (N=168) were 65 years old (standard deviation [SD] 10), 46% were female, with a diabetes duration of 13 years (SD 9) and body mass index of 31 kg/m (SD 6.5). Mean (SD) TST and SLAT were 7.5 (1.0) hours and 9.9 (7.6) minutes, respectively, SEFF was 82.7 (6.1) percent and WASO was 86.7 (53.4) minutes. An inverse association between TST and PCS was found where every additional 60 minutes of sleep was associated with 1.3-unit lower PCS (P=.04). SEFF was positively associated with both PCS and MCS, where a 10% greater SEFF was associated with 2.6-unit higher PCS (P=.008), and 1.8-unit higher MCS (P=.056).
Among this population, better sleep efficiency was associated with better physical and mental health.
睡眠是 2 型糖尿病患者代谢控制和心理健康的重要行为。本研究旨在探讨 2 型糖尿病患者客观估计的睡眠量和睡眠质量与健康相关生活质量（HRQL）的关系。
参与者完成了一项调查，使用 EQ-5D-5 L 指数评分和 SF-12 v2 评估 HRQL，SF-12 v2 提供身体和精神综合摘要（PCS 和 MCS）评分。参与者还在睡眠期间佩戴腕部活动记录仪（Actigraph GT3X+），以得出总睡眠时间（TST）、睡眠潜伏期（SLAT）和睡眠效率（SEFF）以及睡眠后醒来（WASO）的估计值。使用调整后的多变量线性回归模型来检查活动记录仪衍生的睡眠参数与 PCS、MCS 和 EQ-5D-5 L 指数评分之间的关联。
平均而言，参与者（N=168）年龄为 65 岁（标准差[SD] 10），46%为女性，糖尿病病程为 13 年（SD 9），体重指数为 31kg/m（SD 6.5）。平均（SD）TST 和 SLAT 分别为 7.5（1.0）小时和 9.9（7.6）分钟，SEFF 为 82.7（6.1）%，WASO 为 86.7（53.4）分钟。TST 与 PCS 呈负相关，每增加 60 分钟的睡眠与 PCS 降低 1.3 分相关（P=.04）。SEFF 与 PCS 和 MCS 均呈正相关，SEFF 增加 10%与 PCS 升高 2.6 分相关（P=.008），与 MCS 升高 1.8 分相关（P=.056）。
在该人群中，更好的睡眠效率与更好的身心健康相关。
