Wellcome Trust Centre for Neuroimaging,University College London,London WC1N 3BG,United
Princeton Neuroscience Institute,Princeton University,Princeton,NJ
Behav Brain Sci. 2016 Jan;39:e206. doi: 10.1017/S0140525X15001776.
Previous work has suggested that an interaction between local selective (e.g., glutamatergic) excitation and global gain modulation (via norepinephrine) amplifies selectivity in information processing. Mather et al. extend this existing theory by suggesting that localized gain modulation may further mediate this effect - an interesting prospect that invites new theoretical and experimental work.
先前的研究表明,局部选择性(例如谷氨酸能)兴奋与全局增益调制(通过去甲肾上腺素)之间的相互作用可增强信息处理中的选择性。Mather 等人通过提出局部增益调制可能进一步介导这种效应,扩展了这一现有理论——这是一个有趣的前景,它邀请了新的理论和实验工作。