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胃束带后腹腔镜袖状胃切除术的中期结果:倾向评分匹配研究。

Medium Term Outcomes of Revision Laparoscopic Sleeve Gastrectomy after Gastric Banding: A Propensity Score Matched Study.

机构信息

Faculty of Medicine, University of New South Wales, 18 High St, Kensington, NSW, 2052, Australia.

Upper Gastrointestinal Surgery Unit, Department of Surgery, St George Hospital, Gray St, Kogarah, NSW, 2217, Australia.

出版信息

Obes Surg. 2023 Jul;33(7):2005-2015. doi: 10.1007/s11695-023-06629-9. Epub 2023 May 22.

Abstract

PURPOSE

Revision bariatric surgery may be undertaken after weight loss failure and/or complications following primary bariatric surgery. This study aims to compare the efficacy and safety of revision laparoscopic sleeve gastrectomy (RLSG) after gastric banding (GB) to those of primary laparoscopic sleeve gastrectomy (PLSG).

MATERIALS AND METHODS

A retrospective, propensity-score matched study was conducted to compare between PLSG (control) patients and RLSG after GB (treatment) patients. Patients were matched using 2:1 nearest neighbor propensity score matching without replacement. Patients were compared on weight loss outcomes and postoperative complications for up to five years.

RESULTS

144 PLSG patients were compared against 72 RLSG patients. At 36 months, PLSG patients had significantly higher mean %TWL than RLSG patients (27.4 ± 8.6 [9.3-48.9]% vs. 17.9 ± 10.2 [1.7-36.3]%, p < 0.01). At 60 months, both groups had similar mean %TWL (16.6 ± 8.1 [4.6-31.3]% vs. 16.2 ± 6.0 [8.8-22.4)]%, p > 0.05). Early functional complication rates were slightly higher with PLSG (13.9% vs. 9.7%), but late functional complication rates were comparatively higher with RLSG (50.0% vs. 37.5%). The differences were not statistically significant (p > 0.05). Both early (0.7% vs 4.2%) and late (3.5% vs 8.3%) surgical complication rates were lower in PLSG patients compared to RLSG patients but did not reach statistical significance (p > 0.05).

CONCLUSION

RLSG after GB has poorer weight loss outcomes than PLSG in the short-term. Although RLSG may carry higher risks of functional complications, the safety of RLSG and PLSG are overall comparable.

摘要

目的

减重手术后体重减轻失败和/或并发症可进行再次手术。本研究旨在比较胃旁路术后腹腔镜袖状胃切除术(RLSG)与初次腹腔镜袖状胃切除术(PLSG)的疗效和安全性。

材料和方法

回顾性、倾向评分匹配研究比较了 PLSG(对照组)患者和胃旁路术后 RLSG(治疗组)患者。采用无替换的 2:1 最近邻倾向评分匹配进行患者匹配。比较两组患者长达五年的减重效果和术后并发症。

结果

144 例 PLSG 患者与 72 例 RLSG 患者进行了比较。36 个月时,PLSG 患者的平均 %TWL 显著高于 RLSG 患者(27.4 ± 8.6 [9.3-48.9]%比 17.9 ± 10.2 [1.7-36.3]%,p < 0.01)。60 个月时,两组的平均 %TWL 相似(16.6 ± 8.1 [4.6-31.3]%比 16.2 ± 6.0 [8.8-22.4]%,p > 0.05)。PLSG 的早期功能性并发症发生率略高(13.9%比 9.7%),但 RLSG 的晚期功能性并发症发生率较高(50.0%比 37.5%)。差异无统计学意义(p > 0.05)。PLSG 患者的早期(0.7%比 4.2%)和晚期(3.5%比 8.3%)手术并发症发生率均低于 RLSG 患者,但无统计学意义(p > 0.05)。

结论

GB 后 RLSG 的短期减重效果不如 PLSG。虽然 RLSG 可能有更高的功能性并发症风险,但 RLSG 和 PLSG 的安全性总体上是相当的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c72/10289990/f029724e3b60/11695_2023_6629_Fig1_HTML.jpg

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