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长期匹配比较原发性和翻修腹腔镜袖状胃切除术。

Long-Term Matched Comparison of Primary and Revisional Laparoscopic Sleeve Gastrectomy.

机构信息

Assuta Medical Center, Tel Aviv, Israel.

The Azrieli Faculty of Medicine Safed, Bar-Ilan University, Ramat Gan, Israel.

出版信息

Obes Surg. 2023 Mar;33(3):695-705. doi: 10.1007/s11695-022-06436-8. Epub 2023 Jan 3.

Abstract

BACKGROUND

Reports of long-term (> 5-15-year) outcomes assessing the safety and efficacy of primary revisional laparoscopic sleeve gastrectomy (LSG) are few.

METHODS

Retrospective long-term comparisons of primary (pLSG) and revisional (rLSG) procedures were matched for gender, age ± 5 years, and body mass index (BMI) ± 5 kg/m. Weight loss, associated medical condition status, and patient satisfaction were evaluated.

RESULTS

Between May 1, 2006, and December 31, 2016, 194 matched patients with severe obesity (mean BMI 44.1 ± 6.7 kg/m; age 44.2 ± 10.0 years, 67.0% female) underwent pLSG (n = 97) or rLSG (n = 97) and were followed for a mean 12.1 ± 1.5 vs 7.6 ± 2.1 years. Respective mean weight regain from nadir was 15.0 ± 14.4 kg vs 11.9 ± 12.2 kg. Respective percent mean total weight loss and excess weight loss were 20.9 ± 12.7% and 51.8 ± 33.1%, and 18.3 ± 12.8% and 43.4 ± 31.6% at last follow-up, with no significant difference between groups. Resolution of type 2 diabetes (HbA1 < 6.5%, off medications) was 23.1% vs 11.1%; hypertension 36.0% vs 16.0%; and hyperlipidemia 37.1% vs 35.3%. Patients in the pLSG group were significantly more satisfied with LSG (59.8% vs 43.3%, p < 0.05) and more likely to choose the procedure again.

CONCLUSIONS

There were no significant differences in long-term weight loss or associated medical condition outcomes in matched pLSG and rLSG patients.

摘要

背景

关于初次修正腹腔镜袖状胃切除术(LSG)的长期(>5-15 年)安全性和疗效的报告很少。

方法

对初次(pLSG)和修正(rLSG)手术进行回顾性长期比较,并按性别、年龄(±5 岁)和体重指数(BMI)(±5kg/m)进行匹配。评估体重减轻、相关疾病状况和患者满意度。

结果

2006 年 5 月 1 日至 2016 年 12 月 31 日,194 例严重肥胖患者(平均 BMI 44.1±6.7kg/m;年龄 44.2±10.0 岁,67.0%为女性)接受了 pLSG(n=97)或 rLSG(n=97)治疗,并随访了平均 12.1±1.5 年和 7.6±2.1 年。各自的体重从最低点的恢复分别为 15.0±14.4kg 和 11.9±12.2kg。各自的平均体重减轻百分比和多余体重减轻百分比分别为 20.9±12.7%和 51.8±33.1%,18.3±12.8%和 43.4±31.6%,两组之间无显著差异。2 型糖尿病(HbA1<6.5%,停药)缓解率为 23.1%和 11.1%;高血压缓解率为 36.0%和 16.0%;高血脂缓解率为 37.1%和 35.3%。pLSG 组的患者对 LSG 明显更满意(59.8%和 43.3%,p<0.05),且更可能再次选择该手术。

结论

在初次 pLSG 和 rLSG 患者中,长期体重减轻或相关疾病状况结果无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a62/9809525/7ccd078bd4f9/11695_2022_6436_Fig1_HTML.jpg

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