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免疫功能正常患者近期感染弓形虫病伴急性心肌心包炎及肌钙蛋白持续升高

Recent Toxoplasmosis Infection With Acute Myopericarditis and Persistent Troponin Elevation in an Immunocompetent Patient.

作者信息

Roubille François, Roubille Camille, Lattuca Benoît, Gervasoni Richard, Vernhet-Kovacsik Hélène, Leclercq Florence

机构信息

CHU Arnaud de Villeneuve, Cardiology Department, Montpellier, France.

CHU Saint Eloi, Internal Medicine Department, Montpellier, France.

出版信息

Cardiol Res. 2012 Aug;3(4):189-191. doi: 10.4021/cr200w. Epub 2012 Jul 20.

DOI:10.4021/cr200w
PMID:28348686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5358212/
Abstract

Although often considered as "begnin", acute infections in young healthy adults can lead to heart inflammation, including acute myocarditis. We report a rare case of myopericarditis in a young immunocompetent adult, in the context of recent toxoplasmosis infection. Clinical presentation was common acute pericarditis, but with risk biomarkers: high troponin I levels and multiple inflammation-compatible images on MR-scan. Diagnosis of myopericarditis was established. In spite of spontaneous favourable clinical evolution, troponin remained elevated. MR-scan is shown; acute myocarditis in the context of an acute toxoplasmosis infection is discussed.

摘要

尽管急性感染在年轻健康成年人中常被认为是“良性的”,但仍可导致心脏炎症,包括急性心肌炎。我们报告了一例年轻免疫功能正常的成年人患心肌心包炎的罕见病例,该病例发生在近期弓形虫感染的背景下。临床表现为常见的急性心包炎,但伴有风险生物标志物:肌钙蛋白I水平升高以及磁共振扫描上多个与炎症相符的影像。心肌心包炎的诊断得以确立。尽管临床症状自发向好演变,但肌钙蛋白水平仍持续升高。展示了磁共振扫描结果,并对急性弓形虫感染背景下的急性心肌炎进行了讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ef6/5358212/7568e5441cd1/cr-03-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ef6/5358212/7568e5441cd1/cr-03-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ef6/5358212/7568e5441cd1/cr-03-189-g001.jpg

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本文引用的文献

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Genetic disorder or toxoplasma myocarditis: a case report of dilated cardiomyopathy with hypertrabeculation in a young asymptomatic woman.遗传性疾病或弓形虫性心肌炎:一名年轻无症状女性扩张型心肌病伴心肌小梁增多的病例报告
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Can troponin elevation predict worse prognosis in patients with acute pericarditis?肌钙蛋白升高能否预测急性心包炎患者的预后更差?
Ann Cardiol Angeiol (Paris). 2010 Feb;59(1):1-7. doi: 10.1016/j.ancard.2009.07.009. Epub 2009 Aug 13.
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[Acute toxoplasmic perimyocarditis in a 67-year-old HIV-negative woman--a case report].[一名67岁HIV阴性女性的急性弓形虫性心包心肌炎——病例报告]
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Fulminant toxoplasmosis causing fatal pneumonitis and myocarditis.暴发性弓形虫病导致致命性肺炎和心肌炎。
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