由……引起的非创伤性角膜炎。 （原文内容不完整，仅能翻译到这种程度）
Non-traumatic keratitis due to .
作者信息
Llamos Reina, Al-Hatmi Abdullah M S, Martínez Gerardo, Hagen Ferry, Velar Rosario, de la Caridad Castillo Pérez Alexeide, Meis Jacques F, Illnait-Zaragozí María T
机构信息
Department of Microbiology, Ophthalmological Institute "Ramón Pando Ferrer", Havana, Cuba.
Fungal Biodiversity Centre (CBS-KNAW) , Utrecht , the Netherlands.
出版信息
JMM Case Rep. 2016 Aug 30;3(4):e005047. doi: 10.1099/jmmcr.0.005047. eCollection 2016 Aug.
INTRODUCTION
The fungal genus is an uncommon cause of human infections. It has been implicated in cutaneous phaeohyphomycosis, artritis and keratitis secondary to traumatic implantation.
CASE PRESENTATION
We report two cases of keratitis due in middle-aged, immunocompetent persons without history of trauma. The aetiological agents were identified based on DNA sequencing. Azoles and echinocandins showed high minimal inhibitory concentrations while amphotericin B was ≤ 0.25 mg l. Both patients failed topical antifungal treatment and needed penetrating keratoplasty with a favourable outcome.
CONCLUSION
caused keratomycosis which did not respond to topical antifungal agents. To the best of our knowledge these are the first reported cases of keratitis due to this fungus in Cuba and Latin-America and highlights the expanding spectrum of fungal agents causing eye infections.
引言
该真菌属是人类感染的罕见病因。它与皮肤暗色丝孢霉病、创伤植入后继发的关节炎和角膜炎有关。
病例报告
我们报告了两例中年免疫功能正常且无创伤史的角膜炎病例。通过DNA测序确定了病原体。唑类和棘白菌素显示出高最低抑菌浓度，而两性霉素B≤0.25mg/l。两名患者局部抗真菌治疗均失败，需要进行穿透性角膜移植术，结果良好。
结论
引起了角膜真菌病，对局部抗真菌药物无反应。据我们所知，这些是古巴和拉丁美洲首次报告的由这种真菌引起的角膜炎病例，突出了引起眼部感染的真菌病原体范围不断扩大的情况。
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