Yilmaz Basak Saracoglu, Agca Alper, Taskapili Muhittin
Department of Ophthalmology, University of Health Sciences Gaziosmanpasa Training and Research Hospital, Istanbul, Turkey.
Department of Ophthalmology, Dunya Goz Hospital, Istanbul, Turkey.
Beyoglu Eye J. 2022 May 27;7(2):121-125. doi: 10.14744/bej.2022.06978. eCollection 2022.
The aim of the study was to present and compare 2 years results of mechanical photorefractive keratectomy (M-PRK) and transepithelial photorefractive keratectomy (T-PRK) for myopia.
One hundred and nine eyes of 55 patients were included in this retrospective study. The mean age of the patients was 26.9±5.2 years. Forty-four eyes (40.4%) had M-PRK and 65 eyes (59.6%) had T-PRK. Follow-up time was 2 years. Refractive errors (RE), uncorrected visual acuity (UCVA), and high-order corneal aberrations were compared.
The mean RE was -2.33±0.88 D and the mean UCVA was 0.24±0.17 logMAR at baseline for M-PRK patients. At month 24, those measurements were changed to -0.27±0.32 D and 0.99±0.04 logMAR. The mean RE was 2.19±0.73 D and the mean UCVA was 0.23 ± 0.15 logMAR at baseline for T-PRK patients. At month 24, those measurements were changed to -0.14±0.32 D and 0.99±0.01 logMAR. The mean REs significantly decreased and the mean UCVA significantly increased after both type of surgeries (all p<0.001). In M-PRK group, 4 mm zone total corneal aberration and 6 mm total-coma-spherical corneal aberrations were statistically significantly increased in post-operative term. In T-PRK group, only 6 mm total-spherical corneal aberrations were statistically significantly increased in post-operative term. There was no serious complication during surgeries or follow-up time.
M-PRK and T-PRK were a safe and effective in the treatment of myopia in 2 years term. Some high-order aberrations may be increase after those treatments.
本研究旨在呈现并比较准分子激光角膜切削术(M-PRK)和经上皮准分子激光角膜切削术(T-PRK)治疗近视的2年效果。
本回顾性研究纳入了55例患者的109只眼。患者的平均年龄为26.9±5.2岁。44只眼(40.4%)接受了M-PRK,65只眼(59.6%)接受了T-PRK。随访时间为2年。比较了屈光不正(RE)、裸眼视力(UCVA)和高阶角膜像差。
M-PRK患者基线时的平均RE为-2.33±0.88 D,平均UCVA为0.24±0.17 logMAR。在第24个月时,这些测量值分别变为-0.27±0.32 D和0.99±0.04 logMAR。T-PRK患者基线时的平均RE为2.19±0.73 D,平均UCVA为0.23±0.15 logMAR。在第24个月时,这些测量值分别变为-0.14±0.32 D和0.99±0.01 logMAR。两种手术类型后平均RE均显著降低,平均UCVA均显著提高(所有p<0.001)。在M-PRK组中,术后4mm区域总角膜像差和6mm总彗差-球差角膜像差在统计学上显著增加。在T-PRK组中,术后仅6mm总球差角膜像差在统计学上显著增加。手术期间或随访期间均未出现严重并发症。
M-PRK和T-PRK在2年的时间内治疗近视是安全有效的。这些治疗后可能会增加一些高阶像差。