Signorelli Salvatore Santo, Ferrante Margherita, Gaudio Agostino, Fiore Valerio
Department of Clinical and Experimental Medicine, University of Catania, I-95123 Catania, Italy.
Department of Medical, Surgical Sciences and Advanced Technologies 'G.F. Ingrassia', University of Catania, I-95123 Catania, Italy.
Mol Med Rep. 2017 May;15(5):3445-3448. doi: 10.3892/mmr.2017.6395. Epub 2017 Mar 24.
The first-time venous thromboembolism (VTE) is less frequent than other thrombotic events, however, both the pulmonary embolism (PE) and the deep vein thrombosis (DVT) show a frequent morbidity. Many factors play as risk situations in determining VTE, and the air exposure to the fine and ultrafine particulate matter (PM) as PM10, PM2.5, PM0.1 is considered. Epidemiological studies have supported this association although both the effective burden of the association and the mechanisms are to date unclear. The PM concentrations and the exposure time are notable as emerging factors. Interestingly, the seasonal climate variations resulted as effective risk factor for appearance of VTE or DVT. There is a need to ameliorate the environment by reducing the air pollution at global scale.
首次发生静脉血栓栓塞症（VTE）的情况比其他血栓形成事件少见，然而，肺栓塞（PE）和深静脉血栓形成（DVT）的发病率都很高。许多因素在决定VTE时起着风险因素的作用，其中包括暴露于细颗粒物和超细颗粒物（PM），如PM10、PM2.5、PM0.1。尽管这种关联的实际影响程度和机制至今尚不清楚，但流行病学研究支持了这种关联。PM浓度和暴露时间是值得注意的新出现的因素。有趣的是，季节性气候变化是VTE或DVT出现的有效风险因素。有必要通过在全球范围内减少空气污染来改善环境。
