Zielins Elizabeth R, Brett Elizabeth A, Blackshear Charles P, Flacco John, Ransom Ryan C, Longaker Michael T, Wan Derrick C
Stanford, Calif.
From the Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, and the Institute for Stem Cell Biology and Regenerative Medicine, Stanford University.
Plast Reconstr Surg. 2017 Apr;139(4):911-914. doi: 10.1097/PRS.0000000000003165.
Cell-assisted lipotransfer has shown much promise as a technique to improve fat graft retention in both mouse and human studies. However, the literature varies as to whether fresh stromal vascular fraction or culture-expanded adipose-derived stromal cells are used to augment volume retention. The authors' study sought to determine whether there was a significant advantage to using adipose-derived stromal cells over unpurified stromal vascular fraction cells in a mouse model of cell-assisted lipotransfer.
在小鼠和人体研究中,细胞辅助脂肪移植作为一种提高脂肪移植保留率的技术已显示出很大的前景。然而,关于使用新鲜的基质血管成分还是培养扩增的脂肪来源基质细胞来增加体积保留率,文献说法不一。作者的研究旨在确定在细胞辅助脂肪移植的小鼠模型中,使用脂肪来源基质细胞相对于未纯化的基质血管成分细胞是否具有显著优势。
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