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撒哈拉以南非洲疟疾媒介控制面临的挑战:种群中的抗性和行为适应性

Challenges for malaria vector control in sub-Saharan Africa: Resistance and behavioral adaptations in populations.

作者信息

Sougoufara Seynabou, Doucouré Souleymane, Backé Sembéne Pape M, Harry Myriam, Sokhna Cheikh

机构信息

URMITE (Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes), UM63, CNRS 7278, IRD 198, INSERM 1095, IHU - Méditerranée Infection, Marseille; Département de Biologie Animale, Faculté des Sciences et Techniques/Université Cheikh Anta Diop, Dakar Sénégal, France.

URMITE (Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes), UM63, CNRS 7278, IRD 198, INSERM 1095, IHU - Méditerranée Infection, Marseille, France.

出版信息

J Vector Borne Dis. 2017 Jan-Mar;54(1):4-15.

Abstract

Over the past decade, global malaria-related mortality has declined dramatically because of combined international actions that have defined and prioritized national and regional efforts to reduce the incidence of malaria, with the ultimate goal of eradication. Vector control strategies using insecticide-treated nets (ITNs) and indoor residual spraying (IRS) in African countries have contributed significantly to the declining incidence of malaria. However, the effectiveness of malaria control is threatened by increasing insecticide resistance and behavioral changes in Anopheles vectors. Thus, there is an urgent need to ensure that future programmes are designed to address these threats and protect the progress made so far in controlling malaria. This review summarizes the current malaria vector control tools and discusses about the critical threats to vector control programme and vector management.

摘要

在过去十年中,由于一系列国际行动明确了国家和地区减少疟疾发病率努力的重点,并以根除疟疾为最终目标,全球与疟疾相关的死亡率大幅下降。非洲国家采用经杀虫剂处理的蚊帐(ITN)和室内滞留喷洒(IRS)的病媒控制策略,对疟疾发病率的下降做出了重大贡献。然而,疟疾控制的成效受到杀虫剂抗性增强和按蚊病媒行为变化的威胁。因此,迫切需要确保未来的规划旨在应对这些威胁,并保护迄今在控制疟疾方面取得的进展。本综述总结了当前的疟疾病媒控制工具,并讨论了病媒控制规划和病媒管理面临的重大威胁。

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