低镁血症及其与肥胖中慢性低度炎症的关系。
Hypomagnesemia and its relation with chronic low-grade inflammation in obesity.
作者信息
Oliveira Ana Raquel Soares de, Cruz Kyria Jayanne Clímaco, Severo Juliana Soares, Morais Jennifer Beatriz Silva, Freitas Taynáh Emannuelle Coelho de, Araújo Rogério Santiago, Marreiro Dilina do Nascimento
机构信息
PhD Student in Food and Nutrition, Universidade Federal do Piauí (UFPI), Teresina, PI, Brazil.
MSc Student in Food and Nutrition, UFPI, Teresina, PI, Brazil.
出版信息
Rev Assoc Med Bras (1992). 2017 Feb;63(2):156-163. doi: 10.1590/1806-9282.63.02.156.
INTRODUCTION
: The accumulation of visceral fat in obesity is associated with excessive production of proinflammatory adipokines, which contributes to low-grade chronic inflammation state. Moreover, the literature has shown that mineral deficiency, in particular of magnesium, has important role in the pathogenesis of this metabolic disorder with relevant clinical repercussions.
OBJECTIVE
: To bring updated information about the participation of hypomagnesemia in the manifestation of low-grade chronic inflammation in obese individuals.
METHOD
: Articles published in PubMed, SciELO, LILACS and ScienceDirect, using the following keywords: "obesity," "magnesium" and "low grade inflammation."
RESULTS
: Scientific evidence suggests that magnesium deficiency favors the manifestation of low-grade chronic inflammation in obese subjects.
CONCLUSION
: From literature data, it is evident the participation of magnesium through biochemical and metabolic reactions in protecting against this metabolic disorder present in obesity.
引言
肥胖症中内脏脂肪的积累与促炎脂肪因子的过度产生有关，这会导致低度慢性炎症状态。此外，文献表明矿物质缺乏，尤其是镁缺乏，在这种具有相关临床影响的代谢紊乱的发病机制中具有重要作用。
目的
提供有关低镁血症在肥胖个体低度慢性炎症表现中所起作用的最新信息。
方法
在PubMed、SciELO、LILACS和ScienceDirect上发表的文章，使用以下关键词：“肥胖症”、“镁”和“低度炎症”。
结果
科学证据表明，镁缺乏有利于肥胖受试者低度慢性炎症的表现。
结论
从文献数据来看，很明显镁通过生化和代谢反应参与预防肥胖症中存在的这种代谢紊乱。
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