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Metabolites in aging and autophagy.

作者信息

Schroeder Sabrina, Zimmermann Andreas, Carmona-Gutierrez Didac, Eisenberg Tobias, Ruckenstuhl Christoph, Andryushkova Aleksandra, Pendl Tobias, Harger Alexandra, Madeo Frank

机构信息

Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria.

Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria. ; Division of Endocrinology and Metabolism, Dept. of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.

出版信息

Microb Cell. 2014 Apr 7;1(4):110-114. doi: 10.15698/mic2014.04.142.

DOI:10.15698/mic2014.04.142
PMID:28357231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5349198/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a3/5349198/980ecb22655a/mic-01-110-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a3/5349198/980ecb22655a/mic-01-110-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a3/5349198/980ecb22655a/mic-01-110-g01.jpg

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本文引用的文献

1
Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification.通过甲硫氨酸限制延长寿命需要自噬依赖性的液泡酸化。
PLoS Genet. 2014 May 1;10(5):e1004347. doi: 10.1371/journal.pgen.1004347. eCollection 2014 May.
2
Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.能量代谢物乙酰辅酶A的核质耗竭会刺激自噬并延长寿命。
Cell Metab. 2014 Mar 4;19(3):431-44. doi: 10.1016/j.cmet.2014.02.010.
3
Regulation of autophagy by cytosolic acetyl-coenzyme A.
乙酰辅酶 A 羧化酶 1 依赖性脂肪生成促进 AMPK 下游的自噬。
J Biol Chem. 2019 Aug 9;294(32):12020-12039. doi: 10.1074/jbc.RA118.007020. Epub 2019 Jun 17.
4
Influence of Normal Aging on Brain Autophagy: A Complex Scenario.正常衰老对大脑自噬的影响：一个复杂的情况。
Front Aging Neurosci. 2019 Mar 11;11:49. doi: 10.3389/fnagi.2019.00049. eCollection 2019.
5
Antiproliferative activities of the second-generation antipsychotic drug sertindole against breast cancers with a potential application for treatment of breast-to-brain metastases.第二代抗精神病药物塞替派醇对乳腺癌的抗增殖活性及其在治疗乳腺癌脑转移中的潜在应用。
Sci Rep. 2018 Oct 25;8(1):15753. doi: 10.1038/s41598-018-33740-0.
6
Some Metabolites Act as Second Messengers in Yeast Chronological Aging.一些代谢物在酵母时序老化中充当第二信使。
Int J Mol Sci. 2018 Mar 15;19(3):860. doi: 10.3390/ijms19030860.
7
Guidelines and recommendations on yeast cell death nomenclature.酵母细胞死亡命名法指南与建议。
Microb Cell. 2018 Jan 1;5(1):4-31. doi: 10.15698/mic2018.01.607.
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Non-genetic impact factors on chronological lifespan and stress resistance of baker's yeast.非遗传因素对面包酵母按时间计算的寿命和抗逆性的影响
Microb Cell. 2016 Apr 12;3(6):232-235. doi: 10.15698/mic2016.06.504.
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The crucial impact of lysosomes in aging and longevity.溶酶体在衰老和长寿中的关键影响。
Ageing Res Rev. 2016 Dec;32:2-12. doi: 10.1016/j.arr.2016.04.009. Epub 2016 Apr 26.
细胞质乙酰辅酶 A 对自噬的调控。
Mol Cell. 2014 Mar 6;53(5):710-25. doi: 10.1016/j.molcel.2014.01.016. Epub 2014 Feb 20.
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Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging.丝氨酸和苏氨酸/缬氨酸依赖性的PDK和Tor直系同源物激活作用汇聚于Sch9，以促进衰老。
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J Exp Med. 2013 Sep 23;210(10):2119-34. doi: 10.1084/jem.20130252. Epub 2013 Sep 16.
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Tryptophan metabolism: entering the field of aging and age-related pathologies.色氨酸代谢：进入衰老和与年龄相关疾病的领域。
Trends Mol Med. 2013 Jun;19(6):336-44. doi: 10.1016/j.molmed.2013.02.007. Epub 2013 Apr 2.
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Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis.甲硫氨酸补救途径和 S-腺苷甲硫氨酸：硫、乙烯和多胺生物合成之间的重要联系。
Biochem J. 2013 Apr 15;451(2):145-54. doi: 10.1042/BJ20121744.
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Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast.自噬和亮氨酸促进酵母在热量限制下的时序长寿和呼吸能力。
Exp Gerontol. 2013 Oct;48(10):1107-19. doi: 10.1016/j.exger.2013.01.006. Epub 2013 Jan 18.
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Autophagy mediates caloric restriction-induced lifespan extension in Arabidopsis.自噬介导了拟南芥中热量限制引起的寿命延长。
Aging Cell. 2013 Apr;12(2):327-9. doi: 10.1111/acel.12048. Epub 2013 Feb 28.