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非遗传因素对面包酵母按时间计算的寿命和抗逆性的影响

Non-genetic impact factors on chronological lifespan and stress resistance of baker's yeast.

作者信息

Sauer Michael, Mattanovich Diethard

机构信息

Department of Biotechnology, BOKU - VIBT, University of Natural Resources and Life Sciences, Vienna, Muthgasse 18, 1190 Vienna, Austria. ; Austrian Centre of Industrial Biotechnology, Muthgasse 11, 1190 Vienna, Austria.

出版信息

Microb Cell. 2016 Apr 12;3(6):232-235. doi: 10.15698/mic2016.06.504.

DOI:10.15698/mic2016.06.504
PMID:28362008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5348990/
Abstract

Survival under nutrient limitation is an essential feature of microbial cells, and it is defined by the chronological lifespan. We summarize recent findings, illustrating how crucial the choice of the experimental setup is for the interpretation of data in this field. Especially the impact of oxygen supply differs depending on the culture type, highlighting the differences of alternatives like the retentostat to classical batch cultures. Finally the importance of culture conditions on cell aging and survival in biotechnological processes is highlighted.

摘要

在营养限制下存活是微生物细胞的一个基本特征，它由群体寿命来定义。我们总结了近期的研究发现，阐明了实验设置的选择对于该领域数据解读的关键程度。特别是氧气供应的影响因培养类型而异，凸显了恒化器等替代方法与传统分批培养之间的差异。最后强调了培养条件对生物技术过程中细胞衰老和存活的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f38b/5348990/3299a4763f58/mic-03-232-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f38b/5348990/3299a4763f58/mic-03-232-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f38b/5348990/3299a4763f58/mic-03-232-g01.jpg

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本文引用的文献

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Microb Cell. 2015 Mar 2;2(3):62-67. doi: 10.15698/mic2015.03.191.
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Oxygen availability strongly affects chronological lifespan and thermotolerance in batch cultures of .氧气供应强烈影响分批培养物中的时序寿命和耐热性。
Microb Cell. 2015 Oct 21;2(11):429-444. doi: 10.15698/mic2015.11.238.
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