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身体脂肪指数而非内脏脂肪指数与肥胖型肌少症老年女性的炎症标志物相关。

Body Adiposity Index, but not Visceral Adiposity Index, Correlates with Inflammatory Markers in Sarcopenic Obese Elderly Women.

作者信息

Dutra Maurílio Tiradentes, Gadelha André Bonadias, Nóbrega Otávio Toledo, Lima Ricardo Moreno

机构信息

a College of Physical Education , University of Brasília , Brasília , Brazil.

b State Department of Education of the Federal District , Brasília , Brazil.

出版信息

Exp Aging Res. 2017 May-Jun;43(3):291-304. doi: 10.1080/0361073X.2017.1298959.

DOI:10.1080/0361073X.2017.1298959
PMID:28358295
Abstract

UNLABELLED

Background/Study Context: The association of body adiposity index (BAI) and visceral adiposity index (VAI) with inflammatory markers has yet to be understood. The aim of this work was to investigate the association of BAI and VAI with inflammatory markers in elderly women with sarcopenic obesity (SO).

METHODS

A total of 130 women (age: 66.7 ± 5.2 years) underwent body composition analysis by dual-energy x-ray absorptiometry (DEXA). Volunteers were classified according to SO definition. BAI, VAI, and waist-to-hip ratio (WHR) were calculated. Blood samples were collected for C-reactive protein (CRP), tumor necrosis factor, and interleukin-6 (IL-6) measurements.

RESULTS

SO prevalence was 20.8%. BAI correlated with the DEXA-derived body fat content (r = .90), CRP (r = .55), and IL-6 (r = .53), whereas WHR correlated with CRP (r = .60) only (all p < .01). VAI did not correlate with any of the inflammatory variables.

CONCLUSION

Simple and cheap anthropometric indices such as BAI and WHR may be better predictors of low-grade inflammation than VAI in elderly women with SO.

摘要

未标注

背景/研究背景:身体肥胖指数(BAI)和内脏肥胖指数(VAI)与炎症标志物之间的关联尚不清楚。本研究的目的是调查BAI和VAI与老年肌少症肥胖(SO)女性炎症标志物之间的关联。

方法

共有130名女性(年龄:66.7±5.2岁)通过双能X线吸收法(DEXA)进行身体成分分析。志愿者根据SO定义进行分类。计算BAI、VAI和腰臀比(WHR)。采集血样检测C反应蛋白(CRP)、肿瘤坏死因子和白细胞介素-6(IL-6)。

结果

SO患病率为20.8%。BAI与DEXA得出的体脂含量(r = 0.90)、CRP(r = 0.55)和IL-6(r = 0.53)相关,而WHR仅与CRP相关(r = 0.60)(所有p < 0.01)。VAI与任何炎症变量均无相关性。

结论

在患有SO的老年女性中,诸如BAI和WHR等简单且廉价的人体测量指数可能比VAI更能预测低度炎症。

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