早产和足月妊娠子痫前期引产的成功率。
Success of labor induction for pre-eclampsia at preterm and term gestational ages.
作者信息
Roland C, Warshak C R, DeFranco E A
机构信息
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
出版信息
J Perinatol. 2017 Jun;37(6):636-640. doi: 10.1038/jp.2017.31. Epub 2017 Mar 30.
OBJECTIVE
Determine the impact of gestational age (GA) on vaginal delivery following induction of labor (IOL) for pre-eclampsia, and evaluate factors that influence successful induction.
STUDY DESIGN
Population-based retrospective cohort of 1 034 552 live births in Ohio (2006-2012). The rate of vaginal delivery in women with pre-eclampsia who underwent induction was calculated with 95% confidence intervals, stratified by week of GA at birth. Factors associated with the decision to undergo IOL, and success of IOL were evaluated, and multivariable logistic regression estimated the strength of association.
RESULTS
18 296 (71.3%) of the patients who underwent IOL had a vaginal delivery. The majority achieved vaginal delivery at both preterm (66% at 23-36 weeks) and term GAs (72%). Factors most strongly associated with vaginal delivery following IOL for pre-eclampsia included prior vaginal delivery and young maternal age.
CONCLUSION
The majority of women with pre-eclampsia who undergo IOL achieve vaginal birth, even at early GAs.
目的
确定孕周（GA）对先兆子痫引产（IOL）后阴道分娩的影响，并评估影响引产成功的因素。
研究设计
基于人群的回顾性队列研究，纳入俄亥俄州1034552例活产（2006 - 2012年）。计算先兆子痫引产女性的阴道分娩率，并给出95%置信区间，按出生时的孕周分层。评估与决定进行引产及引产成功相关的因素，并通过多变量逻辑回归估计关联强度。
结果
18296例（71.3%）接受引产的患者经阴道分娩。大多数患者在早产（23 - 36周时为66%）和足月孕周时均实现了阴道分娩（72%）。与先兆子痫引产后宫内分娩最密切相关的因素包括既往阴道分娩和产妇年龄较轻。
结论
大多数接受引产的先兆子痫女性实现了阴道分娩，即使在孕周较早时也是如此。
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