a Department of Medical Microbiology, Faculty of Health Sciences , University of Pretoria , Pretoria , South Africa.
b Department of Medical Microbiology, Tshwane Academic Division , National Health Laboratory Service (NHLS) , Pretoria , South Africa.
Crit Rev Microbiol. 2017 Nov;43(6):651-667. doi: 10.1080/1040841X.2017.1291579. Epub 2017 Mar 30.
Microorganisms in nature rarely exist in a planktonic form, but in the form of biofilms. Biofilms have been identified as the cause of many chronic and persistent infections and have been implicated in the etiology of bacterial vaginosis (BV). Bacterial vaginosis is the most common form of vaginal infection in women of reproductive age. Similar to other biofilm infections, BV biofilms protect the BV-related bacteria against antibiotics and cause recurrent BV. In this review, an overview of BV-related bacteria, conceptual models and the stages involved in the polymicrobial BV biofilm formation will be discussed.
自然界中的微生物很少以浮游生物的形式存在，而是以生物膜的形式存在。生物膜已被确定为许多慢性和持续性感染的原因，并与细菌性阴道病（BV）的病因有关。细菌性阴道病是育龄妇女最常见的阴道感染形式。与其他生物膜感染类似，BV 生物膜使与 BV 相关的细菌免受抗生素的影响，并导致 BV 的反复发作。在这篇综述中，将讨论与 BV 相关的细菌、概念模型以及多微生物 BV 生物膜形成所涉及的阶段。
